San Diego-based biotechnology developer Ignyta has acquired fellow, San Diego biotechnology developer Actagene, a developer of personalized medicines based on cancer genome mining and sequencing. Financial details of the acquisition were no...

San Diego-based eFFECTOR Therapeutics said today that it has raised $45M to go towards the development and invention of small molecule drugs, specifically aimed at treating cancer. According to the firm, the Series A investment included U.S...

Santa Monica-based healthcare messaging provider TigerText has linked up with a provider of mobile security, AirWatch, the firms said this week. According to the companies, the move will allow healthcare customers to secure both their mobil...

What's the best way to connect physicians with their patients? A new, Glendale-based startup, SnapMD, is hoping to do that through a smart phone, tablet, or your home PC, via a new service. The firm has just raised $175,000 in a seed fundin...

Santa Barbara-based Active Life Scientific, a developer of life sciences research and diagnostics tools, said this morning that it has raised $500K in a Series A follow on investment. The funding came from members of the Tech Coast Angels. ...

San Diego-based Ambit Biosciences has priced its IPO, saying that it is offering up 8,125,000 shares of its common stock at $8.00 per share. The company will start trading today on the NASDAQ Global Market as AMBI. Ambit priced well below i...

San Diego-based Ambit Biosciences has priced its IPO, saying that it is offering up 8,125,000 shares of its common stock at $8.00 per share. The company will start trading today on the NASDAQ Global Market as AMBI. Ambit priced well below i...

Los Angeles-based Kite Pharma, a biotechnology company developing immunotherapies for cancer, said today that it has raised $35M in its Series A funding round. The firm said that the funding came from Alta Partners, David Bonderman, Pontifa...

Thousand Oaks-based biotech giant Amgen said Thursday that it is in a joint venture with Chinese company Zhejiang Beta Pharma, to commercialize the firm's Vectibix (panitumumab) product in the Chinese market. Financial arrangements of the j...

Carlsbad-based biopharmaceuticals developer Isis Pharmaceuticals reported Thursday that it has received $3.5M in a milestone payment, from Biogen Idec. The company said the payment was received as part of a Phase 2 study milestone of a trea...

San Diego-based biopharmaceuticals developer Receptos is trading flat after its initial public offering, after pricing last night at $14.00 per share. The developer of biopharmaceuticals for treating immune and metabolic diseases priced at ...

San Diego-based Lumena Pharmaceuticals announce today that it has raised $23M in a Series A funding round, to go towards developing oral therapeutics for rare liver diseases. The funding came from Pappas Ventures, RiverVest Venture Partners...

Newport Beach- and Philadelphia-based InstaMed, which operates an online electronic payment clearinghouse for the healthcare industry, said today that it has raised an internal round of funding. Size of the round was not announced. The firm...

Publicly held biotherapeutics developer Arrowhead Research said this morning that it has raised $36M in a private offering. The Pasadena-based company said the new financing was led by RA Capital, and included new investors Camber Capital, ...

San Diego-based Ambit Biosciences has set the estimated range for its IPO, saying in a filing today that it is expecting to offer 4,645,000 shares of its stock at between $13.00 and $15.00 per share. The firm has applied to list on the NASD...

San Diego-based biopharmaceuticals firm Ligand said today that it has acquired a portfolio of potential future milestone and royalty payments for more than 15 biologic development programs from Selexis SA. Financial details of the buy were ...

Irvine-based PathCentral, which operates an online community for pathologists, said today that the Johns Hopkins University School of Medicine has joined its online information exchange and consultation forum. Financial impact of the win wa...

San Diego-based biopharmaceuticals developer Receptos has set the initial, estimated pricing range for its IPO, saying in a filing Thursday that it now expects its IPO pricing to be between $14.00 and $16.00 a share. THe firm, which has app...

In a bid to help bring its products to market, San Diego-based Topera Medical said Thursday that it has raised $25M in a Series C financing, which will go towards its 3D analysis and mapping system for treating atrial fibrillation. The new ...

San Diego-based life sciences equipment firm Illumina said Monday that it has appointed Charles Dadswell as its new Senior Vice President and General Counsel. Dadswell was most recently VP, GEnreal COunsel for North and Latin America, and C...

Studio City-based Seechangehealth has raised a $15.0M funding round, from Psilos Group and Maverick Capital for its health plans and technology geared around preventative care. The Series C investment was actually disclosed in January, but ...

Monrovia, California-based biotherapeutics technology developer Xencor said Tuesday that it has licensed its Xtend technology to an Australian firm. Xencor and CSL Limited said they are in a technology license agreement, which will provide ...

San Diego-based biopharmaceuticals firm Ambit Biosciences announced this morning that it has tapped a venture partner from New Enterprise Associates for a new board member. Ambit said it has named David R. Parkinson, M.D. to its board of di...

San Diego-based biopharmaceuticals firm Receptos has filed for an IPO, saying in a filing that it is looking to raise up to $86.3M in an offering on the NASDAQ Global Market. The firm said it intends to list as "RCPT". The firm's IPO is bei...

Long Beach-based aesthetic medicine developer Obagi Medical Products, and would-be acquirer Valeant Pharmaceuticals, which is based in Aliso Viejo, said this morning that Valeant has raised its offer to acquire Obagi to $24.00 per share in ...

San Diego-based Algenetix, a startup, industrial biotechnology firm, announced this morning that it has raised $2.0M in a Series A-1 funding. The firm said it is developing technology which improves the oil productivity in microbes, for the...

San Diego-based life sciences equipment maker Illumina has been ordered to pay $96M to Syntrix Biosystems, in a patent litigation suite, the company said Thursday. Illumina said a federal jury in Tacoma, Washington found that its BeadChip a...

Los Angeles-based aesthetic medicine developer KYTHERA Biopharmaceuticals announced today that it has named Frederick Beddingfield, III, as its Chief Medical Officer. Dr. Beddingfield is a dermatologist, who was most recently at Allergan, w...

Aliso Viejo-based Avanir Pharmaceuticals, which is developing treatments for central nervous system disorders, said today that it has added Ms. Corinne Nevinny to its board of directors. Nevinny is General Partner at venture capital firm LM...

San Diego-based ADVENTRX Pharmaceuticals announced this morning that it has renamed itself Mast Therapeutics. The firm also said it has swapped its ticker symbol to MSTX on the NYSE market. The firm, which is developing treatments for sickl...

San Diego-based biopharmaceuticals developer Sorrento Therapeutics announced today that it has signed an exclusive option to acquired Fountain Valley-based IGDRASOL, a company developing oncologic agents for treating metastatic breast cance...

San Diego-based pharmaceuticals contract manufacturer Althea Technologies said today that it has been acquired by Japanese company Ajinomoto Co.. Financial terms of the buy were not disclosed. Althea Technologies provides biopharmaceutical ...

San Diego-based Carolus Therapeutics, a developer of biopharmaceuticals aimed at treating acute and chronic inflammation, has scored $2.25M in a debt funding round, according to financing provider Square 1 Bank. According to Square 1, the n...

Is Amgen the next source of the healthcare industry's venture capital deals? It might be, on news that Kevin Sharer, the former CEO of Thousand Oaks-based Amgen, has joined venture capital investment firm Foundation Medical Partners. Accor...

Los Angeles-based private equity investor The Gores Group announced this morning that it has completed the acquisition of GE Healthcare STrategic Sourcing, from GE Healthcare. Financial terms of the buy were not disclosed. GE Healthcare Str...

San Diego-based Qualcomm said this morning that its subsidiary, Qualcomm Life, has joined with health information site WebMD. According to the companies, the two have linked to enable consumers to access and manage their wireless health dat...

San Diego-based personalized medicine developer Ignyta has raised $1M in funding, via a capital term loan from Silicon Valley Bank, the company disclosed this morning. The firm--which is focusing on treating rheumatoid arthritis (RA), lupus...

Valencia-based Sanguine Biosciences, a startup developing a service around blood sample collection for research and development, said Thursday that it has closed on a seed financing round. Size of the round was not announced. The funding wa...

San Diego-based Ambit Biosciences has filed for an IPO, saying in an S-1 with the SEC that it is looking to raised $57.5M in a funding round. The firm said it intends to list as AMBI on the Nasdaq Global Market. The IPO is being underwrit...

Garden Grove-based Hybor Biomedical, which manufactures and markets in vitro diagnostic products for the autoimmune and allergy market, has sold its urinalysis business to an affiliate of One Rock Capital Partners, Laurel Crown Partners, an...

Irvine-based health monitoring products developer Masimo announced a win at the University of Virginia Medical Center, the firm announced this morning. Masimo said that the center is using its Hemoglobin (SpHb) and Acoustic Respiration Rate...

Irvine-based Aviir, a life sciences startup developing laboratory tests for cardiovascular disease, said today that it has signed a distribution and expansion pact covering 19 Middle Eastern and North African countries. Aviir said it has in...

Goleta-based medical device developer BAROnova announced this morning that it has raised a big, $27.3M funding round to fund clinical trails for its weight loss device. The firm said the Series C funding was led by Sante Ventures and Boston...

Calabasas-based network testing equipment and software firm Ixia announced this week that it has launched a new effort with its Wi-Fi testing product, specifically aimed at the health care market. The firm said it has expand its Wi-Fi testi...

San Diego-based PURE Bioscience, which develops antimicrobial products, said earlier this week that it has named Dave Pfanzelter to its board of directors. Pfanzelter was previously a Senior Vice President at Kellogg Company, and also serve...

San Diego-based Receptos, a developer of treatments for immune and metabolic disease, said this week that it has named Graham Cooper as its Chief Financial Officer. Cooper has previously served as CFO of Geron Corporation and Orexigen Thera...

San Diego-based Elcelyx Therapeutics, a developer of treatments for weight management and obesity-related disorders, said this morning that it has raised $20M in a Series C funding round. The financing was led by GSM Fund LLC, and also incl...

Irvine-based Aviir, a developer of cardiovascular disease testing technology, said today that it has raised $10M in a second financing tranche, after meeting a revenue milestone. According to Aviir, the round was led by Merck Global Health ...

Laguna Hills-based Glaukos, which is developing a medical device for treating glaucoma, said this week that it has raised $30M in a funding round. The Series F funding was led by Meritech Capital Partners, and also included Versant Ventures...

Health Data Vision, a new startup based in Burbank, said this week that it has raised a Series A funding round, to go towards its software-as-a-service platform for medical records analysis. Size of the funding was not announced, however,...

Sotera Wireless, the developer of medical devices for wirelessly monitoring patients, has raised $14.8M in a funding round, the firm said this morning. The funding round came from Safeguard Scientifics, and also included Delphi Ventures, Sa...

Ivantis, an Irvine-based developer of treatments for glaucoma, said today that it has raised $27.0M in a Series B funding round. According to Ivantis, the round was led by Ascension Health Ventures, and also included prior investors New Ent...

DRX, a provider of web-based shopping and enrollment software for Medicare health plans, which was based in Los Angeles, has been acquired by Wisconsin-based Connecture, the companies said today. Connecture develops sales automation technol...

Irvine-based Allergan and MAP Pharmaceuticals said this morning that Allergan has agreed to acquire MAP Pharmaceuticals, in a deal worth approximately $958M. Allergan said it will pay $25.00 per share for publicly held MAP Pharmaceuticals. ...

Carlsbad-based scientific instruments manufacturer Life Technologies said this morning that it has acquired BAC BV, a Netherlands-based firm focused on the discovery, development and manufacture of protein purification products. Financial t...

Carlsbad-based Life Technologies said this morning that it has hired two investment banking firms, Deutsche Bank Securities Inc. and Moelis & Company LLC, to assist it in what it called an "annual strategic review". However, according to a ...

Thousand Oaks-based biotech giant Amgen said this week that it is planning to build a new manufacturing facility in Singapore, and will invest approximately $200M in the new plant. Amgen said the new facility will be located in the Tuas Bio...

NantHealth, the advanced, next-generation healthcare services startup which is part of NantWorks, the startup incubation effort of billionaire Dr. Patrick Soon-Shiong, has raised $6.1M in a funding round, according to a regulatory filing by...

Torrance-based Pelican Products, the manufacturer of protective cases, flashlights and portable lighting systems, and other products, has acquired Minnesota Thermal Science (MTS), a developer of temperature controlled packaging solutions. F...

San Diego-based Independa, the developer of software tools to help seniors live longer on their own, said Wednesday that it has rolled out its Independa Angela social engagement product on the Samsung Mobile Galaxy Tab 2. The firm, which is...

Thousand Oaks-based biotech seed developer Ceres said today that it has hit a milestone in its field evaluations, showing that its technology has been demonstrated to provide double-digit percentage increases in yield under drought conditio...

A new, biotech startup focused on delivery of nucleic acid therapeutics, Solstice Biologics, said last week that it has licensed technology developed at UC San Diego, and received $18M in a Series A funding. Solstice, which is based in San ...

San Diego-based PatientSafe Solutions, a developer of mobile platforms used for running healthcare operations and accessing patient data, said today that it has raised $20M in a Series C funding round. The round was led by Merck Global Heal...

San Diego-based life sciences equipment firm Illumina said over the weekend that it is in an agreement to acquire Verinata Health, a provider of non-invasive testing for fetal chromosomal abnormalities. Illumnina said it would pay $350M plu...

San Diego-based Ambrx, a biopharmaceuticals company developing antibodies and proteins, including a Phase 2b growth hormone compound, said today that it has named Lawson Macartney as President and CEO of the company. Macartney also joins th...

San Diego-based ADVENTRX Pharmaceuticals announced this morning that it has named Brandi L. Roberts as its Chief Financial Officer and Senior Vice President. Roberts has been VP, Finance at the company since March of 2011, and also has serv...

San Diego-based BioSurplus, a supplier of pre-owned scientific instruments and equipment, has raised $1.75M in a debt financing. The debt financing was announced over the holidays, and came from Square 1 Bank. Terms of the debt were not ann...

QuestCor Pharmaceuticals, the Anaheim-based biopharmaceuticals firm providing treatments for autoimmune and inflammatory disorders, said yetserday that it has acquired BioVectra, a supplier of contract manufacturing services to the pharmace...

San Diego-based Ignyta has raised $6M in a Series B funding, the firm said over the holidays. The firm said the funding included $5.5M in a Series B equity funding and $500,000 in a capital term loan from Silicon Valley Bank. The first clos...

San Diego-based Independa, the developer of electronics products and software to help seniors live independently longer, has raised $5M in its Series A funding round, the firm announced this morning. The firm said the funding came from City...

San Diego-based Qualcomm Ventures, the venture capital arm of Qualcomm, has backed goBalto, a developer of clinical trial workflow software. goBalto said it raised $12M in a Series B funding, which was led by Singapore Economic Development ...

San Diego-based AwarePoint has raised $4.0M, part of an ongoing, $10.4M funding round, according to a regulatory filing by the firm. The filing indicates the round is a convertible round for the company, and includes JAFCO Technology Partne...

Cal-X Stars Business Accelerator, a startup accelerator group which has been ramping up in Santa Monica, said Friday that it is planning to present its class of medtech companies in San Francisco as part of the Founder Club DEMO day. The ac...

Irvine-based PathCentral, the provider of tools and technology to the pathology community, said today that it sold its diagnostic laboratory business to Ascend Clinical, a provider of end-stage renal disease laboratory testing. Financial te...

San Diego-based MEI Pharma, a publicly traded developer of oncology drugs, said today that it has completed a $27.5M private placement. The new funding was led by Vivo Ventures and New Leaf Venture Partners. MEI Pharma said the new funding ...

ACADIA Pharmaceuticals, which is developing treatments for central nervous system and neurological disease, said this morning that it has received funding from Fast Forward LLC, a nonprofit established by the National Multiple Sclerosis Soc...

San Diego-based venture capital firm Domain Associates and its Russian partner, Rusnano, have put part of their $760M, late stage investment fund to work, investing a total of $93M in funding in three portfolio companies of Domain. The two ...

Irvine-based Allergan said today that it has completed its $350M acquisition of Carlsbad-based SkinMedica, the developer of aesthetic skin care products. The acquisition had been announced on November 12th. As part of the acquisition, SkinM...

Irvine-based AtheroNova, the biotech working on treating atherosclerotic plaque, reported this morning that it has named Dr. Mark K. Wedel as its Senior Vice President of Clinical Affairs, and Chief Medical Officer. Wedel has previously ser...

Irvine-based Masimo, the developer of pulse oximeters used for measuring oxygen levels in patients, has connected its devices to the iPhone, iPad, and iPod touch. The company said its iSpO2 pulse oximeter cable and sensors connect to the de...

San Diego-based biopharmaceuticals firm ACADIA Pharmaceuticals said today that it has raised $86.4M in a private placement. Source of the new funding was not announced. The firm said the new funds will go towards completing its Phase III pr...

San Diego-based Cadence Pharmaceuticals said this morning that it has entered into an agreement to terminate an option it has to acquire Incline Therapeutics. Cadence said it will receive approximately $13M from The Medicines Company to ter...

San Diego-based Somaxon, a developer of treatments for insomnia, has been acquired by Pernix Therapeutics Holdings, in a deal worth $25M. According to the two companies, Pernix will acquire Somaxon in a stock-for-stock transaction worth a t...

Thousand Oaks-based biotech Amgen is acquiring Iceland-based deCODE Genetics, in a deal worth $415M in cash, the two companies announced this morning. deCODE Genetics is a provider of human genetic research which was founded in 1996. deCODE...

San Diego-based Avelas Biosciences has raised $7.65M in a Series A funding round, which it says will go towards clinical studies for its technology for real-time tumor visualization. The funding came from Avalon Ventures. Avelas is developi...

San Diego-based Biomatrica, a developer of technology for stabilizing DNA, RNA, and protein samples, has raised $5M in a funding round, the firm said today. Source of the new funding was not announced. Biomatrica develops ambient temperatur...

Santa Monica-based biopharmaceuticals startup ArmaGen Technologies announced Thursday afternoon tha tit has raised $17M in a Series A financing round. The firm said it is developing brain-penetrating recombinant protein therapeutics, which ...

La Jolla-based Regulus Therapeutics', which is developing microRNA therapeutics in the oncology, fibrosis, hepatitis C and metabolic diseases areas, said yesterday that it has named Victor Knopov as its Vice President, Pharmaceutical Develo...

San Diego-based Volcano Corporation, a developer of diagnostic tools for treating coronary and peripheral vascular disease, said Friday that it has acquired Sync-Rx Ltd., an Israeli software firm developing image processing products.Financi...

San Diego-based MabVax Therapeutics, a developer of immunotherapies aimed at preventing recurrent cancer, said today that it has raised $5.25M in a funding round. The round was led by Numoda Capital Innovation, and also included Burrill Cap...

Carlsbad-based SkinMedica, the developer of aesthetic medicine products, is being acquired by Irvine-based Allergan in a $350M deal, the two said today. Allergan said it will buy SkinMedica $350M up front, plus up to $25M based on future sa...

Irvine-based Biosynthetic Technologies, a firm developing synthetic biomolecules from plant oils, has raised $7M in funding from Monsanto, in addition to other funding from BP Ventures and other investors, the firm said recently. The compan...

San Diego-based Epic Sciences, a firm developing cancer diagnostics technology, announced today that it has raised $13M in a Series B equity round. The round came from Domain Associates, Roche Venture Fund, and Pfizer Venture Investments, a...

Laguna Hills-based Vessix Vascular, a deveveloper of percutaneous radiofrequency (RF) balloon catheter technology being targeted at treating hypertension, has been acquired by Boston Scientific Corporation, the two said this morning. The de...

San Diego-based Auspex Pharmaceuticals announced this morning that it has raised $25M in a funding round, a Series D financing for the company. The round was led by Panorama Capital, and also included Thomas, McNerney & Partners, CMEA Capit...

San Diego-based Ambit Biosciences announced this morning that it has raised $25M in the first tranche of a $50M preferred stock financing. The round will go towards supporting its lead drug candidate. The round was led by Orbimed Advisors, ...

Los Angeles-based Genesis Digital Imaging, a developer of imaging software for the diagnostic imaging systems market, has been acquired by CareStream, a manufacturer of healthcare imaging, X-ray systems, and other related products. Financia...

La Jolla-based biopharmaceuticals firm Regulus Therapeutics, which is developing microRNA-based biopharmaceuticals aimed at oncology, fibrosis, hepatitis C and metabolic diseases, said it has raised $80.9M in total proceeds from its IPO, a ...

Carlsbad-based life sciences equipment company Life Technologies announced today that it has acquired Advanced Microscopy Group, a developer of imaging systems for research microscopy. Financial terms of the buy were not disclosed. Life Tec...

Thousand Oaks-based Amgen and venture firm Kleiner Perkins Caufield & Byers have put their backing behind a new, Westlake Village based drug development firm, Atara Biotherapeutics, in an unusual spinout of technology from the biotech giant...

San Diego-based Thesan Pharmaceuticals said today that it has raised $16M in a Series A round, for the firm's developing of treatments for dermatological disorders. The firm said the funding was co-led by Novo Ventures and Novartis Venture ...

San Diego-based Reflexion Health, a new startup using Microsoft's Kinect for physical therapy products, has raised $4.25M in a funding round, the company said this morning. Reflexion Health said the funding came from West Health Investment ...

Santa Monica-based text messaging provider TigerText reported Thursday that it now has more than 250 healthcare facilities using its HIPAA compliant messaging platform. The firm, which provides secure text messaging for enterprise customers...

The acquisition of Vista, California-based Aperio by German firm Leica Biosystems has completed, the firms said Thursday. Aperio, a maker of digital pathology and slide digitization systems, and Leica had announced the deal on August 21st. ...

Santa Ana-based Health Essentials, a provider of post-acute care for the frail and elderly, has scored a round of growth capital from two Silicon Valley venture investors. Health Essentials said it raised a round of funding from SV Life Sci...

Los Angeles-based NanHealth, the subsidiary of NantWorks, the incubator of LA billionaire Dr. Patrick Soon-Shiong, has scored an investment from Verizon Investments, the investment arm of Verizon Communications. Size of the funding was not ...

Carlsbad-based pharmaceuticals developer Isis Pharmaceuticals said Tuesday afternoon that it will receive $1.1M from Alnylam Pharmaceuticals, as a resutl of upfront fees from Alnylam's collaboration with Genzyme. Isis said the additional pa...

San Diego-based Independa, the provider of technology which helps to connect and remotely monitor seniors, to help them live independently longer, has raised $1M in an angel funding round. The funding was first publicly disclosed in a regul...

San Diego-based Accelrys, which develops software for the life sciences industry, has acquired a fellow software company, Aegis Analytical. Accelrys said it paid $30M for Colorado based Aegis, which it will use to bolster its products. Aegi...

La Jolla-based Cebix, a biopharmaceutcials company that is developing treatments for complications due to diabetes, said this week that it has raised $30.9M in a Series B investment round. The funding came from its existing investors, which...

San Diego-based Fate Therapeutics announced this morning that it has named Christian Weyer, M.D., M.A.S., as its new President and CEO. Weyer joins the firm from Amylin Pharmaceuticals. Weyer had been serving as SVP Research and Development...

San Diego-based healthcare investor Domain Associates has made an investment in a Philadelphia provider of hospital discharge planning and readmission management software this week, RightCare Solutions. RightCare said it has raised $1.72M ...

Laguna Hills-based LoneStar Heart, a firm developing cardiac restorative therapies for patients with heart failure, has raised $20M in a funding round, the firm revealed today, from Chinese investor Themes Investment Partners. The firm said...

Carlsbad-based life sciences equipment firm Life Technologies said Monday that it has acquired Compendia Bioscience, a developer of cancer bioinformatics products. Financial terms of the buy were not disclosed. Compendia's products are used...

San Diego-based Regulus Therapeutics has adjusted its anticipated IPO terms, saying in a filing this morning that it now anticipates its initial public offering price of its stock to be $4.00 per share, and that it will offer up 11.25M shar...

San Diego-based Vital Therapies, a biotechnology firm focused on treatments for acute liver failure, said Thursday that it has raised $16M, part of a $76M mult-stage commitment to the firm by its investors. The firm said the funding will go...

Azusa-based Contour Energy Systems, the venture backed developers of advanced battery systems, said today that it is targeting the medical device market with its products. The firm said its Li/CFx battery cells are particularly well-suited ...

San Diego-based Cytori Therapeutics, a developer of cell therapy products aimed at treating cardiovascular disease and repairing soft tissue, said today that it has been awarded a contact worth up to $106M. The contract came from the U.S. ...

San Diego-based Freedom Meditech, a developer of opthalmic medical devices being used to detect disease and measure patient health, said Thursday that it has secured a $2M line of credit. The credit line came from Silicon Valley Bank. Terms...

Vista-based AutoGenomics has filed for an IPO, saying that it is looking to raise up to $65M in a public offering on the NASDAQ Global Market. The maker of molecular diagnostics systems--used by reference laboratories, hospitals and special...

Calabasas-based KYTHERA Biopharmaceuticals, a venture-backed developer of aesthetic medicine products, has set its IPO pricing range, saying earlier this week that it is expectings its IPO price to be between $14.00 and $16.00 per share. KY...

Irvine-based Paragon Biomedical, a contract research organization (CRO), has been acquired by Clinipace, the two announced today. Financial terms of the acquisition were not disclosed. The two companies said the acquisition will "significan...

San Diego-based Skylight Healthcare Systems, a developer of interactive patient care systems, said today that it has raised $5.0M in a funding round. The Series D round came from Duchossois Capital Partners. Skylight said the funding will g...

Irvine-based Aviir, a developer of laboratory tests for detecting cardiovascular disease, said it has raised $8M in funding from Silicon Valley Bank. The firm said the round included $5M in growth debt, plus a $3M line of credit. The new fu...

San Diego-based Illumina, the developer of life sciences tools, said this morning that it has acquired BlueGnome, a UK-based provider of in-vitro fertilization and cytogenetics screening products. Financial terms of the acquisition were not...

San Diego-based Sense4Baby, a brand new starting spawned out of the West Health Institute, has licensed a wireless fetal monitoring system from West Health, and moved into that firm's new incubator. West Health Institute also said that Sens...

Carlsbad-based Life Technologies, which develops genetic analysis and other scientific instruments, said today that it has entered into a partnership with Bristol-Myers Squibb. According to the company, the two will work on companion diagno...

Los Angeles-based Response Genetics, a publicly held provider of molecular diagnostic testing services for cancer, announced this morning that it has raised $8.8M in a private placement of its stock. The new funding came from GlaxoSmithKli...

San Diego-based GlySens, a startup developing implantable, long-term glucose monitoring sensors, has scored an investment round, according to investor West Health Investment Fund. Financial terms of the investment were not disclosed. La Jol...

Exagen Diagnostics, a venture-backed developer of molecular diagnostics testing which operates its main laboratory in Vista, California, said it has raised $5.3M. The funding was led by Tullis Health Invesotrs, and also included Sun Mountai...

How would you like to receive "frequent flyer" points for visiting your doctor or dentist? That's just what Los Angeles-based Health In Reach announced this morning, saying that it has launched a reward program where users can earn free den...

San Diego-based Sequenom, the developer of life sciences and genetic testing equipment, said today that it has added Myla Lai-Goldman, M.D., to its board of directors. Lai-Goldman is Managing Partner at Personalized Science LLC, CEO of Gene...

San Diego-based Elevation Pharmaceuticals, the venture backed developer of treatment for patients with chronic obstructive pulmonary disease (COPD), has been acquired by Masachussets-based Sunovion Pharmaceuticals, in a deal worth up to $43...

Santa Barbara-based BioIQ, the developer of software and technology for the health and wellness industry, said today that it has partnered with privately held insurance brokerage and consulting firm Keenan. BioIQ said that its health screen...

Carlsbad-based biopharmaceuticals firm Isis Pharmaceuticals, which is developing treatments for Crohn's disease and other rare diseases, said this morning that it will receive $1.4M from Alnylam Pharmaceuticals. The payment comes as part of...

Vista-based Aperio, the developer of digital pathology equipment, is being acquired by German company Leica Biosystems, the companies said today. Financial details of the buy were not announced by the companies. The two said the move will h...

Publicly held biopharmaceuticals firm MediciNova, which is based in San Diego, said last night that it has raised $20M in funding in a deal with Aspire Capital Fund, LLC. Medicinova said that Aspire will purchase the $20M in common stock at...

San Diego-based Regulus Therapeutics has filed for an IPO, saying that it is looking to raised up to $57.5M in an IPO on the NASDAQ Global Market. The developer of microDNA-based biopharmaceuticals said it hopes to trade as RGLS. The IPO is...

Long Beach-based Obagi Medical Products, a developer of aesthetic medicine products, said Thursday that it has named Mark T. Taylor as its Senior Vice President, Corporate Development and Investor Relations. Taylor joins the firm from Roth ...

A new, Los Angeles startup, FitKit--started by a team of doctors and computer science students at UCLA--is launching today, looking to help make nutrition advice personal for online users. The company, which was incubated in the StartEngine...

San Diego-based ADVENTRX Pharmaceuticals announced this morning that it has named Santosh J. Vetticaden, M.D., Ph.D., as its new Chief Medical Officer and Senior Vice President. The firm said Vetticaden was most recently at Cubist Pharmaceu...

San Diego-based Elcelyx Therapeutics, a developer of biopharmaceuticals aimed at both the weight loss and diabetes area, said this morning that it has raised $4M of a $7M extension of its Series B equity funding round. The new funding came ...

Monrovia, California-based Prolacta Bioscience, the venture-backed company which is turning donated breast milk into human milk fortifier for premature babies, reported this week that it has donated more than $1M to various charitable organ...

Thousand Oaks-based Amgen said late Wednesday that it has terminated a Phase 3 study of a drug it is developing to treat metastatic pancreatic cancer, after a recommendation by the independent committee overseeing the trial. The firm said t...

San Diego-based renewable chemicals developer Genomatica has dropped its IPO plans, according to a regulatory filing by the company this morning. The firm, which had filed for a $100M IPO in August of 2011, said in a withdrawal of its regis...

San Diego-based Independa, the remote healthcare monitoring service aimed at helping the elderly live independently longer, is continuing to expand out its partnerships with equipment makers, saying today that it has linked with IDEAL LIFE,...

Carslbad-based Life Technologies said today that it has acquired Pinpoint Genomics, a developer of an early-stage, non-small cell lung cancer test. Financial terms of the buy were not announced. Pinpoint's tests help identify early-stage pa...

San Diego-based CoDa Therapeutics, which develops biopharmaceuticals aimed at wound care, said today that it has added $20M to its Series B financing round. The new funding, a second close, came from RusnanoMedInvest. CoDa Therapeutics said...

Los angeles-based NantWorks, the technology thinktank of Los Angeles billionaire Dr. Patrick Soon-Shiong, said Tuesday that one of its companies, NantPharma, has received $125M in an investment by private equity firm Blackstone. NantPharma ...

San Diego-based Life Technologies, the maker of life sciences equipment, has signed on as the first competitor in the Archon Genomics X PRIZE, the life sciences prize being administered by Marina Del Rey-based X Prize Foundation. The compet...

San Diego-based Obalon said Wednesday afternoon that it has raised $16.5M, in a Series C funding. The funding was led by InterWest Partners, and also included Domain Associates and Okapi Venture Capital. Obalon is a developer of gastric ba...

San Diego-based BioSurplus, a provider of equipment management services and pre-owned laboratory instruments, said this morning that it has closed its Series A financing round, bringing the total raised in the oversubscribed round to $2.4M....

Carlsbad-based life sciences equipment maker Life Technologies announced late Monday that it has acquired Navigenics, a venture-backed genetics diagnostic testing firm and lab. Navigenics was venture backed by Kleiner Perkins Caulfield and ...

San Diego-based Gen-Probe, the developer of molecular diagnostics products, and Massachusetts-based Hologic announced this morning that the two firms have received clearance from Germany's Federal Cartel Office for the acquisition of Hologi...

Irvine-based Micardia, a developer of medical devices used for treating cardiovascular diseases, said Tuesday that it has raised a round of funding, which will provide it with $4.4M during 2012 and 2013. The firm said the round was an inter...

Engineers at the University of California, Los Angeles have created the world's fatest camera, and are using it to help detect cancer cells and detecting disease, the school said last week. UCLA said that the team at the UCLA Henry Samueli...

Thousand Oaks-based biotech giant Amgen said Thursday that it has completed its acquisition of KAI Pharmaceuticals, the South San Francisco-based developer of treatments for treating secondary hyperparathyroidism in patients with chronic ki...

Two Southern California venture investors have re-upped their investment in a Northern California maker of spin repair devices, Benvenue Medical. Benvenue said it raised $25M in a Series D funding yesterday, led by its existing ivnestors, w...

Laguna Hills-based Sonnendo, a firm developing medical devices for the use in root canals (endodontic therapy), said Thursday that it has raised $9.2M in an initial close of a $20M equity funding. e firm said the round was led by OrbiMed Ad...

The Tech Coast Angels, the largest angel investment group in Southern California, has backed a developer of treatments for the flu., According to Gemmus Pharma, it raised an angel funding round led by the Life Science Angels, and also inclu...

Carlsbad-based Medsphere Systems, which develops open source, electronic health record (EHR) software, said this morning that it has named Mike Morotti as its Vice President of Sales. Morotti was previously at Validus Medical Systems, and a...

San Diego-based Pathway Genomics, the venture backed provider of genetic testing services, reported a win this morning with a Brazilian medical diagnostics company. Pathway Genomics said it has tied with Diagnosticos da America, which it sa...

Aliso Viejo-based Avanir Pharmaceuticals, the biopharmaceuticals firm focused on treatments for central nervous system disorders, has received $30M in a debt funding round, according to lenders Oxford FInance and Silicon Valley Bank. Avanir...

San Diego-based Ambrx, a venture backed biopharmaceuticals firm, said this morning that it has entered into a deal with Merck. Ambrx said the deal with Merck is to design and develop rationally optimized biologic drug conjugates based on Am...

Carlsbad-based Life Technologies, the developer of molecular diagnostics and other tools for the life sciences industry, said today that it has set up shop in Singapore. The firm said it has opened a Global Instrument Center of Excellence i...

Thousand Oaks-based biopharmaceuticals firm Amgen said Tuesday afternoon that it has completed its acquisition of Turkish biopharma Mustafa Nevzat Pharmaceuticals. The acquisition, which had originally been announced on April 25th, was wort...

San Diego-based Qualcomm has re-upped its investment in a maker of an electriocardiogram (ECG) device which connects into iPhone, iPad, and Android devices. According to AliveCor, which is based in San Francisco, it has raised $10.5M in a s...

Lake Forest-based ReVision Optics, the venture backed developer of a implantable lens which reduces the need for reading glasses i patients with presbyopia, said it has advanced into its Phase 3, clinical trials with its corneal inlays. The...

San Diego-based Astute Medical, a provider of biomarker-based medical diagnostics technology, reports this morning that it has raised $40.4M in a Series C funding round. The round was led by MPM Capital, and also included new investor Kaise...

Carlsbad-based Medsphere, the developer of electronic health records systems, said today that it has named Lily S. Chang as its Chief Technology Officer. Chang was most recently CTO at Advent Software, where she had run the firm's technolog...

San Diego-based Optimer Pharmaceuticals said this morning that it has named Stephen Webster as the firm's new Chief Financial Officer. Webster was previously CFO of Adolar Corporation, and also served at Broadpoint Capital (formerly First A...

San Diego-based Awarepoint, which develops real-time, location systems used for tracking patents and assets in a healthcare environment, said today that it has raised $14M in an additional financing round. The firm said the round was led by...

San Diego-based biopharmaceuticals firm Sangart has raised $50M in a Series G funding round, the company announced Thursday, bringing its total venture funds raised to $280M. Sangart, which is developing biopharmaceuticals to treat hemorrha...

Makucell, a life sciences company developing anti-aging skin products, said this morning that it has appointed Kevin J. Scanlon, Ph.D., to its board of advisors. Scanlon is Chairman of the Pasadena Angels and also an active member of the Te...

Biofuels and renewable chemical technology firm Verdezyne announced Wednesday that it has named a new Chief Business Officer. The firm said that Ray W. Miller, who was at DuPont from 1972 through 2011, has joined the firm to head up busines...

San Diego-based BioSurplus, a provider of pre-owned, laboratory instruments for the life sciences industry, said today that it has raised $1.5M in a capital raise for an expansion into Boston. The firm said the funding came from KI Investme...

Carlsbad-based Verdezyne, which is developing biotechnology used for biofuels production and chemicals manufacturing, has raised $10.6M in a new, debt funding round, according to a filing from the firm last week. Details on the funding have...

San Diego-based Celladon, a biopharmaceuticals firm developing a genetically targeted enzyme replacement therapy which helps in the treatment of late-stage, heart failure, has raised $53M in a second close of a funding round, the firm said ...

San DIego-based molecular diagnostics equipment maker Gen-Probe, which is publicly held, is being acquired by Hologic in a $3.7 billion deal, the firms said this morning. The two said that Hologic will pay $82.75 per share in cash for Gen-P...

Three of the venture investors in publicly held Orexigen Therapeutics are departing the board of directors of the company, Orexigen said Friday, as the firm shuffled its board. Orexigen said that Joseph Lacob, Michael Powell, and Daniel Tur...

The Tech Coast Angels has backed the maker of a medical device to help people with severe disabilities to walk. According to Cadence Biomedical, the Tech Coast Angels are among a number of new investors in a $1.1M, Series A2 funding for the...

Irvine-based Quality Systems, a provider of practice management and electronic health records software, said today that it has acquired Matrix Management Solutions, a reseller of revenue cycle management and electronic health records produc...

San Diego-based RainTree Oncology Services, a provider of systems which help oncologists to purchase oral drugs, manage inventories, track prescriptions, and monitor patients, has raised $11.1M, the firm said late Tuesday. The firm said the...

Thousand Oaks-based Amgen said this morning that it has acquired Turkish pharmaceuticals firm Mustafa Nevzat Pharmaceuticals. Amgen said the deal is worth $700M in cash. Amgen said the acquisition will help to significantly expand its prese...

San Diego-based Independa, which develops remote health management and monitoring systems for the elderly, said today that it has raised $2.35M in a convertible note funding. The firm said the round included Miramar Venture Partners and Cit...

Lake Forest-based Revision Optics, which is developing implantable micro-lens technology for treating presbyopia, said today that it has named a new board member. The firm said it has added Stephen Slade, M.D., FACS, to its board. Slade is ...

Santa Barbara-based Inogen, a provider of oxygen therapy equipment and services, said Thursday that it has scored a $20M, equity funding round. The round was led by Novo A/S. Inogen, which is led by Raymond Huggenberger, said the new funds ...

San Diego-based Tioga Pharmaceuticals, a developer of biopharmaceuticals for treating irritable bowel syndrome, said today that it has raised $10M in a Series B funding round. The round was led by Thomas, McNerney & Partners, which also inc...

Thousand Oaks-based biotech giant Amgen said this morning that it has agreed to buy KAI Pharmaceuticals, a developer of treatments for secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) who are on dialysis, f...

Aliso Viejo-based WaveTec Vision, which is developing diagnostic devices for cataract surgery, said monday that it has raised $16.5M more in funding. The funding was led by Burrill & Company, and also included Versant Ventures, Accuitive Me...

Publicly held San Diego firm Optimer Pharmaceuticals, a developer of biopharmaceutical products, appears to be in the midst of a major executive overhaul. According to the firm this morning, its board has removed Dr. Michael Chang as Chairm...

Computer software giant Microsoft has rolled out a video of a bunch of Xbox 360-playing, dancing senior citizens in Los Angeles, as part of an effort to promote a new program with the City of Los Angeles Department of Aging. Microsoft said ...

Monrovia-based Xencor, the developer of antibody technology which is headed by Dr. Bassil Dahiyat, said today that it has received a second, milestone payment from Boehringer Ingelheim. Financial details and amount of the payment were not d...

San Diego-based Illumina, the developer of genetics analysis and other life sciences tools, has again rejected an unsolicited bid from Roche to take over the company. Roche had upped its offer for Illumina to $51.00 last week, up from an ea...

San Diego-based Genalyte, a developer of life sciences equipment which uses silicon chips for protein and nucleic acid testing. said this morning that it has raised $11.8M in a Series B financing round. The round came from Redmile Group, Cl...

Carlsbad-based GenMark Diagnostics, the developer of molecular diagnostics testing systems, reported this morning that it is in a licensing agreement with PerkinElemer. GenMark said it has been granted a non-exclusive license to PerkinElmer...

Santa Barbara-based Sientra, a developer of FDA-approved, silicone breast implants, said Wednesday that it has raised $65M in a Series C funding round. The funding was led by Abingworth, and also included Clarus Ventures, OrbiMed Advisors, ...

Los Angeles-based NantWorks, the business investment and development firm run by billionaire Patrick Soon-Shiong, has invested $30M in Strand Diagnostics, a developer of a diagnostic and DNA testing service for diagnosing cancer. According ...

San Diego-based Independa, the developer of remote monitoring products for seniors, is powering a new tablet computer-based remote care service from LivHOME, the two said this morning. LivHOME launched LivIndependa, a remote care and monito...

Los Angeles-based ImaginAb, a UCLA spinout which is developing antibody fragments for use in the diagnostic imaging market, said late last night that it has raised $12.5M in a Series A financing round. The round was led by Novartis Venture ...

Irvine-based ISTA Pharmaceuticals, a manufacturer of products to treat ocular inflammation and pain post-cataract surgery, glaucoma and ocular itching associated with allergic conjunctivitis, has been acquired by Bausche + Lomb in a $500M d...

La Jolla-based Anaphore, a startup biopharmaceuticals developer, said today that it has acquired a Chinese firm, RuiYi Inc., and closed on the second tranche of its Series A financing, worth $15M. Anaphore said it acquired RuiYi to gain acc...

Biopharmaceuticals giant Merck said today that it is investing $90M in setting up a new, San Diego research organization, called Calibr. According to Merck, the new, independent not-for-profit will aim to accelerate translation of basic bio...

Los Angeles-based KYTHERA Biopharmaceuticals, which develops aesthetic medicine products, said this morning that it has named Elisabeth Sandoval as its Chief Commercial OFficer. Sandoval was previously at Bausch + Lomb Surgical, and also ha...

Irvine-based Masimo, the developer of pulse oximetry devices, said today that it is acquiring substantially all of the assets of Spire Semiconductor, a maker of light emitting diode (LED) and other components, which are used in biomedical a...

San Diego-based HemaQuest Pharmaceuticals said today that it has raised $13M in a Series B funding. The firm, which is developing small molecule therapeutics for treating hemoglobin disorders such as sickle cell disease, said the funds come...

San Clemente-based Cameron Health, a maker of subcutaneous, implantable cardiac defibrillators, has been acquired by Boston Scientific, in a deal worth $150M in cash, plus up to $150M on FDA approval of Cameron Health's product, plus up to ...

San Diego-based CareFusion said yesterday that it has agreed a technology and consulting firm focused on pharmacy automation, PHACTS, LLC. Financial terms of the buy were not disclosed. PHACTS, which is based in Seattle, provides consulting...

Aliso Viejo-based Sequent Medical, a developer of medical devices used to treat aneurysms, has raised $26.0M in a venture financing round. The firm said the Series C was led by Delphi Ventures, and also included Versant Ventures, US Venture...

San Diego-based Aragon Pharmaceuticals reports this morning that the firm has raised $42M in a Series C, funding round. The firm, which is developing treatments targeting hormone-driven cancers, said the round was led by Topspin Fund, the i...

Los Angeles-based Nantworks, the new business incubator run by billionaire Dr. Patrick Soon-Shiong, said today that it has acquired another company, Boston Life Labs. Financial terms of the buy were not disclosed. NantWorks said it will ren...

San Diego-based Qualcomm Life, the wireless health-focused subsidiary of Qualcomm, reported today that it has made an investment in wireless healthcare startup AirStrip Technologies. Financial details of the investment were not disclosed. Q...

Santa Barbara-based OWL Biomedical, a developer of microchip-based disposable cell sorting technology for the biomedical industry, has raised $3.0M, part of an ongoing funding with a target of $16.8M, according to regulatory filings. OWL is...

La Jolla-based Celladon Corporation, a developer of biopharmaceuticals targeting cardiovascular disease, said Wednesday afternoon that it has raised $43M in a financing round. The round was led by Pfizer Venture Investments, and also includ...

Carlsbad-based KFX Medical, which is developing bone implant products for the orthopedic surgery market, reported today that it has received a third patent. The patent, U.S. Patent No. 8,109,969, covers its knotless double row soft tissue b...

Westlake Village-based Cynvenio Biosystems, the developer of molecular diagnostics systems for cancer, has spun out a new subsidiary, BioMolded Products, focused on blow molded plastic parts for the biopharmaceutical and life science indust...

San Diego-based Ambit Biosciences, the developer of biopharmaceuticals for the treatment of cancer, inflammatory disease and other conditions, said this morning that it has named a Chief Medical Officer. The company said it has appointed At...

San Diego-based Applied Proteomics, which is developing personalized medicine applications, said today that it has raised $22.5M in a Series B funding, and moved its headquarters to San Diego. The funding came from Domain Associates, Vulcan...

Westlake Village-based Cynvenio Biosystems, which is developing molecular diagnostics systems for cancer, announced this morning that it has received $2.0M in financing, plus scored two Small Business Innovative Research (SBIR) contracts fr...

Santa Monica-based TigerText, a startup providing secure mobile messaging services for healthcare companies, announced today that it has raised $8.2M in a second round of funding. The round was led by Easton Capital and New Science Ventures...

Los Angeles-based Response Genetics, a developer of diagnostics test for cancer, said today that it has raised $7.8M in a private placement. The publicly traded firm did not disclose the name of its new investors. The firm said it sold appr...

San Diego-based life sciences tools developer Illumina said today that its board of directors will be reviewing the usnolicited offer by Roche to acquire the firm, for $44.50 per share in cash. Roche made the offer--which is worth $5.7 bill...

Thousand Oaks-based Amgen announced today that it is acquiring Micromet, a biopharmaceuticals firm based in Germany and Rockville, Maryland, in a deal worth $1.16 billion. Amgen said it will pay $11 per share in cash for Micromet, which is ...

Carlsbad-based KFx Medical said Tuesday that it has scored a U.S. Patent, covering its knotless double row rotator cuff repair technology, which is used in its line of implant products. U.S. Patent No. 8,100,942 was granted by the US Patent...

Carlsbad-based Verdezyne, the venture backed developer of biofuels technology, said today that it has been granted a United States Patent. The firm said the patent, No. 8,093,037, covers its engineered microorganisms used to enable yest to ...

Carlsbad-based SkinMedica, a venture backed cosmaceuticals firm developing skin care products, said Monday that it has acquired Colorescience, a makeup company developing science-based mineral makeups. Financial terms of the buy were not di...

Tustin-based Uptake Medical, the developer of treatments for emphysema led by R. King Nelson, announced today that it has raised a Series C funding round. Size of the round was not announced. The round was led by Crescent Point Group (Singa...

Santa Barbara-based Yardi, which develops software for property management, said Thursday afternoon that it has acquired ALMSA Corporation, a provider of software for the assisted living industry. Financial terms of the buy were not disclos...

Pasadena-based Arrowhead Research and RNAi therapeutics firm Alnylam Pharmaceuticals announced this morning that the two are in a collaboration and licensing agreement. Financial details of the agreement were not announced. THe two said tha...

San Diego-based NeuroGentic Pharmaceuticals, a firm development treatments for Alzheimer's disease, said today that it has scored an investment round from Abbot Biotech Ventures. Size of the round was not announced. NeuroGenetic said the in...

San Diego-based Marshall Edwards, a publicly held firm focused on development of oncology drugs, said Thursday that it has raised $2M in a private placement. The funding came from its majority shareholder, Novogen Limited. Marshall Edwards ...

San Diego-based Metritage Pharma, which is developing drugs for treating chronic inflammatory diseases of the esophagus, is gaining up to $20M from ViroPharma, which is buying an exclusive option to acquire Meritage. ViroPharma said it paid...

Irvine-based Aviir, a venture-backed biotech firm targeting cardiac disease assessment, said late Monday that it has reached an agreement to raise up to $30M in a financing round. The firm said the round includes an initial $10M, plus up to...

Thousad Oaks-based Amgen said Monday that it has inked a $400M, co-development deal with Watson Pharmaceuticals, where they two will work together on oncology antibody biosimilar medicines. The two said that Amgen will assume primarily resp...

San Diego-based Somaxon Pharmaceuticals, a developer of sleep medication, said today that it has cut 60 percent of its non-field based employees, and has hired a financial advisor to help sell the company. The firm said it has hired Stifel ...

San Diego-based Independa, the venture backed provider of health monitoring systems for the elderly, announced this week that it has launched a new set of health, safety, and activity sensors which connect into its services. The company--wh...

Los Angeles-based Tribogenics, a startup working on technology to bring elements of Star Trek's "tricorder" to life, said this morning that it has raised $2.5M in a venture funding round. The firm, a spinoff of UCLA whose technology has bee...

San Diego-based Qualcomm announced this morning that it has created a new, wholly owned subsidiary called Qualcomm Life, which will focus on wireless solutions for the medical devices market. The new subsidiary will also backed by a new, ve...

Orange County-based Harbor MedTech, a developer of wound healing technology, has raised $600,000 in a funding round from private investors, the firm disclosed today, to help the firm grow and further develop its products. Harbor MedTech is ...

San Diego-based eBioscience, a developer of flow cytometry and immunoassay reagents for immunology and oncology research and diagnostics, is being acquired by Affymetrix, Affymetrix said Wednesday. Affymetrix said it is paying $330M in cash...

Carlsbad-based Verdezyne, a developer of biotechnology used to produce renewable chemicals and fuels, announced today that it has opened its first pilot plant. The company said the plant will produce adipic acid, a key component of nylon. T...

Irvine-based AcuFocus, a maker of corneal inlays for treating presbyopia, announced this morning that it has raised $65M in a funding round. The ronud was led by Cowen Healthcare Royalty Partners, and also included SV Life Sciences, Versant...

Los Angeles-based Puma Biotechnology, a developer of biopharmaceuticals aimed at treating cancer, said this morning that it has completed a second tranche of a $60M private financing. The company said that Leerink Swann LLC was the lead pla...

San Diego-based Excaliard Pharmaceuticals, a developer of biopharmaceuticals for treating skin scarring, has been acquired by Pfizer. Financial terms of the buy were not disclosed. Excaliard was venture backed by RiverVest, Alta Partners, P...

La Jolla-based biomedical research nonprofit Scripps Research Institute and IBM said this morning that they are looking for the public's help, in volunteering to donate their computer time to help a new effort to cure malaria, funded by IBM...

Two, Southern California venture investors have scored an exit this morning with the IPO of Clovis Oncology. San Diego's Domain Associates and Newport Beach-based Versant Ventures are both significant investors in Clovis, which priced its I...

San Diego-based Ambit Biosciences said today that it has named Michael A. Martino as its new President and CEO. Ambit, which is developing small molecule kinase inhibitors for the treatment of cancer, inflammatory disease and other indicati...

Two Southern California venture firms are among the investors who are awaiting an expected IPO of Clovis Oncology, a developer of cancer drugs, this week. Clovis Oncology, based in Colorado, is expected to price its IPO this week, according...

Santa Barbara-based InTouch Technologies, which develops telemedicine products, said this morning that it has named Stephen L. Wilson as Executive Vice President and Chief Financial Officer. Wilson was most recently Executive Vice President...

San Diego-based Rempex Pharmaceuticals, a biopharmaceuticals firm addressing antibiotic resistance, announced this morning that it has raised $67.5M in an initial close of a Series B financing round. The round came from Frazier Healthcare V...

La Jolla-based Perminova announced Tuesday that it has raised $7M in a funding round, which it will use to develop its web-based cardiovascular procedure software. Perminova's software provides scheduling, workflow, surgical data, and billi...

San Diego-based ACADIA Pharmaceuticals reported this morning that the U.S. Food and Drug Administration has completed its review of the firm's New Drug Application for AM-831, its small molecule for treatment of schizophrenia, and it is adv...

Monrovia, California-based Prolatca Bioscience, which supplies human milk-based fortifiers for premature infants, said today that it has closed a Series D funding round. The round came from Health Evolution Partners. Size of the round was n...

Los Angeles-based ImagineAb, a spinout of UCLA which is developing diagnostic imaging technology, reported Monday that it has been awarded $2.3M in funding, from the National Cancer Institute's (NCI) Small Business Innovation Research (SBIR...

Pasadena-based Arrowhead Research, which develops biotherapeutics and other technology, announced today that it has named Bruce Given, M.D., as its Chief Operating Officer. Given was previously CEO of Leonardo Biosystems, and also has been ...

Irvine-based Analytix On Demand, a developer of business intelligence software for the healthcare market, said Tuesday that it has acquired healthcare consulting and education firm Integrated Revenue Management, Inc.. Financial terms of the...

Los Angeles-based Nantworks, the business incubation and technology development firm headed by LA billionaire Patrick Soon-shiong, has acquired Ziosoft, a provider of medical imaging and visualization software. According to Ziosoft, which d...

The Chan Soon-Shiong Insitute for Advanced Health--one of the projects of that billionaire Patrick Soon-Shiong--said today, along with Soon-Shiong's incubator NantWorks, that Soon-Shiong has been working on a treatment for advanced metasta...

San Diego-based biotechnology firm Verenium announced this morning that it has scored credit lines totaling $16M, for the development of its enzyme development efforts. The firm said it has entered into an agreement with Comerica Bank and t...

San Diego-based Anadys Pharmaceuticals, the developer of treatments for hepatitis C, said this morning that it has agreed to be acquired by Roche. The firm said it signed a definitive merger agreement where Roche will pay $3.70 per share fo...

Thousand Oaks-based Amgen said Thursday evening that it has added Robert A. Bradway, the firm's current President and Chief Operating Officer, to the company's board. According to Amgen, the addition of Bradway brings its total board member...

Researchers at the California Institute of Technology reported last week that they have created a "smart petri dish" which uses Google smart phones and Lego blocks, to automatically monitor cell growth in petri dishes. In a paper presented ...

Laguna Niguel-based Inspiration Biopharmaceuticals, a developer of treatments for hemophilia, announced today that it has appointed John P. Butler as its new CEO. Butler replaces current CEO Michael Griffith, who becomes Chief Scientific Of...

Carlsbad-based Medsphere Systems, which develops open source healthcare software, said today that it has named John Bright as Vice President of Sales and marketing. Bright joins the company from Henry Schein Medical Systems, and also has se...

San Diego-based CoDa Therapeutics, a developer of biopharmaceuticals for wound care, has scored $6M in a credit facility, according to the firm's lender. Square 1 Bank said that it has provided CoDa Therapeutics with a $6M term loan. Terms ...

San Diego-based ImThera Medical, a developer of medical devices to treat sleep apnea, has raised $16M in an initial funding round from publicly held Cyberonics, plus its other investors Cyberonics said Wednesday. ImThera is developing an im...

San Diego-based private equity firm JMI Equity has invested in Studer Group, a provider of healthcare performance improvement services for hospitals and medical groups. Size of the investment was not disclosed. Financial details of the inve...

San Clemente-based ReShape Medical, a developer of a non-surgical weight loss device, said today that it has named Richard Thompson as the firm's president and CEO. Thompson was previously founder, president, and CEO of Luminous Medical, an...

Monrovia-based Prolacta Bioscience, the venture-backed provider of human milk-based fortifiers for premature infants, said today that it has inked a deal with the National Milk Bank, where the firm will process all of the milk through the b...

La Jolla-based Ambrx, the biopharmaceuticals developer, and Bristol-Myers Squibb said today that the two are in a collaboration. According to the companies, Bristol-Myer Squibb will receive exclusive, worldwide rights to research, develop, ...

In a demonstration of the amount of activity in San Diego's biotech industry, two, separate companies announced new biotech laboratories opened up in San Diego Wednesday. Both Isis Pharmaceuticals and the J. Craig Venter Institute said they...

San Diego-based Independa, which operates a service to help family and professional caregivers monitor loved ones, has raised $1.6M in a seed funding round, the firm said today. The funding came from Miramar Venture Partners and CityHill Ve...

Los Angeles-based KYTHERA Biopharmaceuticals, a developer of aesthetic medicine products, said today that it has raised $37.4M in a series D funding round. The round included new investors Foley Ventures and Latham and Watkins, and also inc...

Carpinteria-based Celerus Diagnostics, a developer of pathology analysis equipment, has now raised $10M in a Series C funding, according to a regulatory filing from the firm Thursday. Details on the funding have not been released by the com...

RF Surgical Systems, a developer of systems used to keep track of surgical sponges during surgery procedures, announced Tuesday that it has raised $12M in funding. The firm--which has its R&D facilities in San Diego--said the round was led ...

In good news for the LA jobs market, another Los Angeles company is reporting big hiring plans. Los Angeles-based Zynx Health, a developer of clincial decision support software for the healthcare market, said today that it has opened up ove...

Thousand Oaks-based biotech giant Amgen has backed a developer of therapeutic antibodies, via its venture capital arm, Amgen Ventures. According to Seattle-based Theraclone Sciences, Amgen Ventures was one of the investors in a $10.6M, Seri...

Tustin-based Uptake Medical, the developer of a minimally invasive treatment for severe emphysema, announced today that it has named Lloyd Mencinger as its European General Manager. Mencinger most recently served at Tenent Healthcare, and a...

Amgen Ventures, the venture capital arm of Thousand Oaks-based Amgen, has backed the developer of a biopharmaceutical aimed at treating irritable bowel syndrome, kidney disease, and diabetes. According to Fremont, California-based Ardelyx, ...

ConjuChem, a biotechnology firm focused on developing medicines based on therapeutics peptides, said today that it has relaunched the company, and is now based in Los Angeles under the management of Patrick Soon-Shiong, M.D. The firm, which...

Santa Barbara-based Inogen, a manufacturer of oxygen therapy products for the home healthcare industry, has scored a $6M credit facility, according to Square 1 Bank. Terms of the credit facility were not announced. Inogen develops home oxyg...

San Diego-based Awarepoint, the developer of real-time, location systems for the healthcare market, announced this morning that it has raised $27M in new financing, as part of a Series F round. The round was led by new investor Kleiner Perk...

San Diego-based Zogenix, the developer of delivery systems for administering pain medication, is planning a follow on offering of its stock. According to an S-1 filed by the firm today, it is selling 12M shares of its common stock, and is l...

Camarillo-based PBS Biotech, a developer of bioreactors for the biotech market, said Tuesday that it has acquired Camarillo-based Integrity CMI, a medical device design and manufacturing companies. Financial terms of the deal were not discl...

Irvine-based Masimo, the maker of pulse oximetry and other medical monitoring devices, has been sued for patent infringement by competitor Essential Medical Devices, Inc.. According to a filing in the Delaware District Court Friday, Essenti...

Laguna Hills-based Sonendo, a developer of dental surgery equipment, has raised $5.9M in a funding round, according to a regulatory filing by the firm this week. According to the filing, the $5.9M is part of an ongoing $6.4M equity round. N...

The Tech Coast Angels, Southern California's biggest and most active angel investing group, appears to be backing a developer of prescription drug validation systems, based in Lebanon, N.H. According to a regulatory filing from PharmaSecure...

Irvine-based Quality Systems, a developer of electronic health records and other health-related IT products, said Wednesday that it has agreed to acquire CQI Solutions, a provider of surgery information systems. Financial terms of the acqui...

San Diego-based Acutus Medical, a developer of medical devices for treating cardiac arrhythmia, said today that it has received $1M in a funding round. The round came form Index Ventures and un-named private investors. Acutus Medical said i...

Aliso Viejo-based Avanir Pharmaceuticals said today that it has named Dr. Joao Siffert as its Senior Vice President Research and Development. Siffert was previously VP and Chief Medical Officer at Ceregene, and has also served at Avera Phar...

Laguna Hills-based Vessix Vascular, a developer of catheter technology, said this week that it has raised $23M in a Series B financing round. The round was led by Edmond de Rothschild Investment Partners (EdRIP), and also included Orbimed A...

San Diego-based KFx Medical, the venture-backed developer of medical devices used for orthopedic surgery, said this week that it has launched a patent infringement suit against a competitor, Arthrex. KFx medical alleges that Arthrex is infr...

Westlake Village-based Cynvenio Biosystems, a developer of medical diagnostics technology, said Wednesday that it has bolstered its board of directors with two appointments. According to Cynvenio, Amit Munshi and Simon Raab have joined the ...

Irvine-based Ellipse Technologies, a developer of minimally invasive treatments for spinal deformities, said Tuesday that it has raised $17.6M in a Series C financing round. The round came form HBM BioVentures and BioStar Ventures, along wi...

San Diego-based CareFusion, the developer of medical devices, said today that it has completed its acquisition of German firm Rowa, a firm which develops robotics medical storage and retrieval systems for pharmacies. The deal was worth $150...

Poway-based Nexus Biosystems, a developer of automated compound and sample management equipment for the life sciences industry, has been acquired by Brooks Automation in a deal worth $79M, the firms said earlier this week. According to Broo...

San Diego-based Amira Pharmaceuticals, a developer of small molecule pharmaceuticals for treating inflammatory and fibrotic diseases, has agreed to be acquired by Bristol-Myers Squibb, the firms said late Thursday. Bristol-Myers Squibb said...

San Diego-based Awarepoint Corporation, the developer of real-time location systems for the hospital market, claimed today that it had a record quarter, booking over forty-six hospitals and health systems. The firm said the number of bookin...

Irvine-based Allergan said this morning that it has acquired Vicept Therapeutics, a developer of a compound for treating the erythema of rosacea. According to Allergan, it will pay $75M in cash up front, plus up to $200M in earnout dependen...

Thousand Oaks-based Amgen said Friday afternoon that it has resolved a patent litigation suite with Teva. The firm said that the United States District Court in Pennsylvania has issued a final judgement and permanent injunction against Teva...

San Diego-based Naviscan, the developer of 3D medical imaging technology, said today that it has added Andre Cheng, M.D., Ph.D., to its board of directors. Cheng has previously served as VP of Medical Affairs and Reimbursement at Acclarent,...

Los Angeles-based Kite Pharma, a biopharmaceuticals firm focused on cancer treatments, announced this morning that it has appointed Adrian Bot, M.D., Ph.D., as its Chief Scientific Officer. Dr. Bot joins the company from MannKind Corp., whe...

Thousand oaks-based biotech giant Amgen said Tuesday that the firm is taking part in a preclinical test on the final, NASA Space Shuttle mission scheduled to launch Friday. According to Amgen, it is in a collaboration with UCB and NASA Ames...

San Diego-based ResMed, a developer of medical equipment for treating sleep disorders, said today that it has acquired Irish medical technology firm BiancaMed Ltd.. Financial terms of the buy were not disclosed. BiancaMed is a developer of ...

San Diego-based CareFusion, the developer of infusion pumps and other medical products, reported today that it is acquiring Rowa, a German firm focused on robotic medical storage and retrieval systems. The deal was worth approximately $150M...

Lake Forest-based Tenex Health, a developer of minimally invasive for treating tendon injuries, said today that it has raised $5M in a series A financing round. The funding was led by VCI Partners. Tenex said the new funding comes on top of...

Costa Mesa-based Experian, the provider of credit information and related services, said today that it has acquired venture-backed Medical Present Value, a provider of revenue cycle management software to physicians. Experian said it would ...

Irvine-based Ivantis, a developer of medical devices for the treatment of glaucoma, announced today that it has raised $17M in a new, second round of funding. The round came from New Enterprise Associates and Delphi Ventures. Ivantis said i...

Hawthorne-based OSI Systems, the developer of specialized electronics products for the security and healthcare industry, reported today that it has won a $3M contract from a New Jersey health system customer. The award went to its healthcar...

In another, Southern California linked IPO, a Colorado anti-cancer firm. Clovis Oncology, has filed for a debut on the NASDAQ Global Market. Clovis Oncology is backed by Southern California investors Domain Associates and Versant Ventures, ...

Thousand Oaks-based Amgen said today that it has awarded 34 science teachers with $10,000 each, in its 19th annual Amgen Award for Science Teaching Excellence. The firm awards the grants each year for "extraordinary" science teachers throug...

San Diego-based Somaxon Pharmaceuticals, a specialty pharmaceuticals firm working on insomnia on other drugs, said today that it has raised $5M in a private placement. The firm said it raised the $5M from Paladin Labs, Inc., and comes in co...

San Diego-based Ambit Biosciences, which is developing cancer treatments, announced this morning that it has raised $30M in Series D-2 round of funding. The funding was led by Apposite Capital LLP, and also included prior investors Perseus-...

Irvine-based Epiomed Therapeutics, a developer of small-molecule, anti-emetic and anti-motion sickness compounds, said this week that it raised a Series A funding round. The firm said the round came from NDI Capital. Financial details of th...

San Diego-based Access Scientific, a developer of vascular access technology, said today that it has completed a $10M, financing round. The round was led by CAC, and also included the firm's prior investors. The firm said the funding will ...

San Diego-based Ambit Biosciences has dropped its IPO plans, according to the firm in a filing with the Securities and Exchange Commission Tuesday afternoon. According to the withdrawal request from Ambit, the firm decided that "terms curre...

Los Angeles billionaire entrepreneur Patrick Soon Shiong has made an investment in a healthcare technology firm Net.Orange, Net.Orange said today. The Texas firm provides a suite of web-based applications for the healthcare industry. Financ...

San Diego-based Otonomy, a firm developing products to treat disorders of the inner and middle ear, looks to have pulled in $14.2M more in a tranched financing which was originally announced last August, according to a regulatory filing by ...

Jake Winebaum is a veteran of the Southern California technology industry, having run and sold a number of successful, Southern California startups. His last success was Business.com, which he sold to R.R. Donnelly, and he also was behind e...

San Diego-based Prometheus Laboratories, a specialty pharmaceuticals and diagnostics firm, has been acquired by Nestle Health Sciences S.A., a subsidiary of Nestle S.A. Financial terms of the deal were not disclosed. The firms said that the...

Hawthorne-based OSI Systems, a manufacturer of specialized electronic systems, reported today that it has scored a $1.6M contract. The firm said its Spacelabs Healthcare unit received the order from a South Carolina hospital, for a line of ...

Vista-based Aperio, which develops digital pathology equipment, said Thursday that it has named Thomas Bologna to its board of directors. Bologna is President and CEO of Orchid Cellmark, a provider of DNA identity testing services. Bologna ...

Vista-based AutoGenomics, a developer of molecular diagnostics hardware, has pulled its IPO, the firm said in a filing Wednesday evening. The firm said it has "elected not to pursue the sale of securities" but did not give a reason for the ...

San Clemente-based Cameron Health, which is developing subcutaneous implantable defibrillators, said today that it has raised $107M in an equity financing round. The round was led by Alloy Ventures and Delphi Ventures. the firm said the fun...

Los Angeles-based biopharmaceuticals firm CytRx said late last night that it has sold off the firm's molecular chaperone assets, to Denmark-based Orphazyme ApS. The deal is worth as much as $120M, if all development and commercialization mi...

Los Angeles-based mobileStorm, the mobile and email messaging and marketing firm headed by Jared Reitzin, said Wednesday that it has launched a new, healthcare focused offering, and signed Humana as a beta client. The firm said its new "mob...

San Diego-based Halozyme Therapeutics, a developer of products for the insulin, cancer, dermatology and drug delivery markets, said today along with ViroPharma Incorporate that it is in a $83M licensing deal. The two said that Halozyme has ...

Los Angeles-based Anti-AgingGames.com, a new startup offering up brain fitness games, has launched today, aiming at healthy people looking to help their memory, concentration, and focus. The site--whose games were designed by Atari founder ...

La Jolla-based NeuroVigil, a firm developing non-invasive wireless brain recording technology and advanced computational analysis techniques, has raised a first round of funding, the firm said this week. Amount of the funding, and source, w...

The Tech Coast Angels, the largest and most active angel investment group in Southern California, is backing a firm developing testing for cervical cancer. According to fellow investor the Sand Hill Angels, OncoHealth Corporation has raised...

Carlsbad-based Life Technologies, the developer of life sciences analysis equipment, said last week that it has named Dr. Ora Hirsch Pescovitz to its board of directors. Pescovitz is Executive Vice President for Medical Affairs and Health S...

San Diego-based TRACON Pharmaceuticals, a firm developing cancer therapeutics, said this morning that it has raised $14M in a first tranche closing of a venture round. The round was led by JAFCO and Nextech Invest, and also included Arcus V...

San Diego-based Sangart, a firm developing products to prevent and treat ischemia and to stabilize the hemoglobin of sickle cell disease patients, said Tuesday that it has raised $50M in a Series G equity financing round. The round was led ...

San Diego-based Awarepoint, the developer of real time location systems for hospitals, said this morning that it has acquired Patient Care Technology Systems (PCTS). Financial terms of the acquisition were not disclosed. PCTS, based in Char...

San Diego-based CoDA Therapeutics, a developer of chronic wound healing biopharmaceuticals, announced this morning that it has raised $19.2M in a series B financing round. The round came from Domain Associates, GBS Venture Partners and BioP...

La Jolla-based Regulus Therapeutics, a biopharmaceuticals firm developing microRNA-based medicines, said this morning that it has named Neil W. Gibson as its Chief Scientific Officer. Gibson joins the firm from PFizer, and previously has se...

San Diego-based Conatus Pharmaceuticals, a biopharmaceuticals firm working on treatments for hepatitis C, said this week that it has closed on an additional $7.5M in its Series B funding round. The round came from MPM Capital. The new fundi...

San Diego-based MabVax Therapeutics, a biotechnology firm developing cancer treatments based on vaccine and antibody based therapies, said this morning that it has received $1.8M in a Phase 2, Small Business Innovation Research award. The a...

Pasadena-based Arrowhead Research said Wednesday that it has boosted its stake in Ablaris Therapeutics, a firm developing treatments for obesity. According to Arrowhead Research, it invested $1.3M in a second close of a Series A financing r...

Inglewood-based Magnetecs, a designer of robotic catherization control systems for minimally invasive surgery, announced today that it has named Clive Zickel as the firm's new Chief Financial Officer. Zickel has previously served at JPMorga...

Laguna Nigel-based Inspiration Biopharmaceuticals, a developer of treatments for hemophilia, has raised its latest funding to $247.6M, according to a regulatory filing by the firm today. Details on the funding have not been announced by the...

San Diego-based Arena Pharmaceuticals, a publicly held developer of pharmaceuticals based on G protein-coupled receptors (GPCRs), announced this morning that it has raised $35.5M in a Series C convertible preferred stock financing. The fund...

Carlsbad-based GenMark Diagnostics, a developer of molecular diagnostic systems, said Thursday that Paul Ross has been appointed as its Chief Financial Officer. Ross joins from Teledata Technology Solutions, and also has been at Meade Instr...

San Diego-based Amylin Pharmaceuticals and partner Takeda Pharmaceutical Company reported this morning that they have suspended clinical activities on a Phase 2 study involving its obesity treatment. The firm said the study was voluntarily ...

San Diego-based TriLink BioTechnologies, a biotech startup working on technology for improving PCR processes, said this morning that it has received a $100,000 Phase I, SBIR Grant from the National Institutes of Health. The firm said the fu...

San Diego-based Astute Medical, a firm working on developing diagnostic test using protein biomarkers, said this week that it has raised $13M in a financing round. The round was a Series B extension. The funding came from Domain Associates,...

Los Angeles-based Kite Pharma, a biopharmaceuticals firm developing treatments for cancer, said this morning that it has raised $15M in an initial round of funding. The funding was led by TPG Capital. As part of the funding, David Bonderman...

Bonita, California-based Anabios, a stealth mode firm working on drug testing services for pain drugs, has scored an angel investment round from the Tech Coast Angels. The funding came from the TCA's new ACE Fund, the angel group's more for...

Irvine-based Pharmaron, a provider of R&D services to the pharmaceutical and biotech industry, said last week that it has raised $40M in a Series C funding round. The round came from DCM, Legend Capital, GL Capital Group, and others. The fi...

Irvine-based Uptake Medical, a developer of non-surgical treatments for lung disease, said today that it has named Scott Huennekens to its board. Huennekens is President and CEO of Volcano Corporation, and also has served at Digirad Corpora...

San Diego- and Baltimore-based private equity firm JMI Equity has invested in PointClickCare, a developer of electronic health records software for the long-term care industry. Financial terms of the deal were not disclosed. PointClickCare ...

San Diego-based Biomatrica, a developer of technology for storing biological samples at room temperature, announced this morning that it has scored an investment from In-Q-Tel, the investment arm of the U.S. intelligence community. Size of ...

La Jolla-based CalciMedica, a developer of small molecule drugs for the treatment of inflammatory and autoimmune diseases, said Thursday that it has raised $6M in a tranche of financing, after initiating a Phase I clinical trial of a treatm...

San Diego-based Orexigen Therapeutics announced this morning that its CFO, Graham Cooper, is resigning from the firm. The company said that Cooper is resigning for personal reasons, and partially because he has been commuting from the San F...

San Diego-based Conatus Pharmaceuticals said Friday afternoon that it has closed a $20M, Series B funding round. The firm, which is developing treatments for Hepatitis C, said the funding was led by AgeChem Venture Fund, and also included A...

San Diego-based Orexigen Therapeutics, which is developing biopharmaceuticals focused on treating obesity, said Wednesday afternoon that it is cutting 40 percent of its staff, or 23 employees. According to Orexigen, the move comes as a resu...

San Diego-based Somaxon Pharmaceuticals said this morning tha tit has scored a $15M, revolving line of credit from Comerica Bank, and also engaged a contract sales force firm. Somaxon said it has tied with Publicis Touchpoint Solutions to r...

Orange County-based Beckman Coulter, a maker of biomedical testing equipment, said today that it is in a merger agreement with Danaher, where Danaher will buy the firm for $6.8 billion. The deal is worth $83.50 per share in cash, which the ...

Lake Forest-based ReVision Optics, which is developing an implantable microlens for treating vision problems, said today that it has named John t. Kilcoyne as its CEO and President. Kilcoyne was most recently Chairman and CEO of Micrus Endo...

Laguna Hills-based Glaukos, which is developing a medical device for the treatment of glaucoma, has raised $29.5M in a Series E round, the firm confirmed Thursday. According to Richard Harrison, the firm's CFO, the funding was led by Merite...

San Diego-based CareFusion, which develops medical products such as pumps, ventilators, patient identification systems, and more, said this morning that it is selling its CareFusion International Surgical Products (ISP) business to Medline,...

San Diego-based Somaxon Pharmaceuticals announced today that it has appointed Robert Cutler as Vice President Business Development. Cutler was most recently at Biogen Idec, having served as Senior Director Business Development, as well as A...

Patrick Soon-Shiong, the Los Angeles area biotech billionaire, has acquired Vitality Corp., a Cambridge, Massachusetts maker of "smart pills." Financial terms of the acquisition were not disclosed. According to Vitality, the acquisition wil...

San Clemente-based VertiFlex, a developer of medical devices for the treatment of spine disorders, said this afternoon that it has raised $14M in a equity placement. The funding came from Aberdare Ventures, Alta Partners, New Enterprise Ass...

Goleta-based BAROnova, a developer of medical devices to treat obesity, has raised another $5.2M in funding, according to numbers released earlier this month in the PricewaterhouseCoopers/NVCA MoneyTree report. The funding has not yet been ...

San Diego-based Ligand Pharmaceuticals said Wednesday afternoon that it has acquired CyDex Pharmaceuticals, a Kansas-based drug reformulation firm. Ligand said it will pay $31.2M in upfront cash, $4.3M at the one year anniversary of closing...

Thousand Oaks-based biotech giant Amgen said Monday afternoon that it is acquiring Biovex, a Woburn, Massachusetts-based developer of treatments for melanoma and head and neck cancer. Amgen said it will pay up to $1 billion for the company,...

San Diego-based Genoptix, a publicly held provider of laboratory services to the hematology and oncology market, said this morning that it is in a definitive merger agreement to be acquired by Novartis. According to Genoptix, the deal is wo...

The Tech Coast Angels, the largest angel investment group in Southern California, is part of a syndicate funding Pittsburgh-based Cognition Therapeutics, a drug discovery firm focused on Alzheimer's. According to Cognition, it raised $2.5M ...

Thousand Oaks-based Amgen said Tuesday afternoon along with Boehringer Ingelheim, that the firm has agreed to sell rights in and substantially all of the assets of its Fremont, Calfiornia development and manufacturing facility. According to...

San Diego-based Illumina, which manufactures genetic sequencing tools for the life sciences industry, said late Tuesday that it has opened up a new office in Sao Paolo, Brazil, to focus on business across Latin America. Illumina said the of...

San Diego-based ADVENTRX Pharmaceuticals said this morning that it has raised $22.5M in funding, via a registered direct offering to RA Capital Management and other investors. According to the publicly traded firm, the new funding will go t...

Thousand Oaks-based Amgen, and Monrovia-based Xencor said Thursday that the two firms are in a co-development dual around a new novel antibody for treating autoimmune diseases. According to the two, Amgen has gained an option to an exclusiv...

San Diego-based Qualcomm said today that the firm's wireless machine-to-machine modules have been designed into a blood glucose meter product from Telcare Incorporated. According to Qualcomm its Internet of Everything Module (IEM) has been ...

Vista-based Aperio, a provider of digital pathology products, said this week that it has named Patrick Yount as its Chief Financial Officer. Yount joins the firm from Univita Health, and has served at Axia Health Management, Biosensors Inte...

Hawthorne-based OSI Systems, a developer and manufacturer of specialized electronic systems, said today that it has received a $3M order from a Washington state hospital. The firm said its Spacelabs Healthcare division received the $3M orde...

Los Angels-based Capricor, a firm developing stem cell technology to regenerate damaged heart tissue, announced Friday that it has raised $2M in a funding round. The round came from Broadview Ventures and individual investors. According to ...

San Diego-based Optimer Pharmaceuticals said today that it has named Gregory Papaz as its Senior Vice President of Commercial Operations. Papaz was most recently at Genentech, and als ohas worked at Roche Pharma, Sanofi-Aventis, and Marion ...

Thousand Oaks-based Amgen, via its nonprofit foundation, the Amgen Foundation, said Friday that it is giving $1.8M to the Teach For America effort. According to the two, the funding will go towards increasing the number of math and science ...

Westlake Village-based Specialists On Call, a firm developing a service to provide physician specialists to urban, suburban, and other hospitals via videoconferencing, has raised around $11.73M in a series of fundings, according to regulato...

San Diego-based Gen-Probe has acquired GTI Diagnostics, a specialty diagnostics firm focused on the transplantation, blood bank and specialty coagulation markets, the firm said Wednesday. The deal was worth $53M in cash. GTI was owned by pr...

Irvine-based Endologix said today that it has completed its acquisition of Nellix, a developer of a medical device for the treatment of Abdominal Aortic Anerysms (AAAs). The acquisition had been originally announced in october. Endologix wi...

Los Angeles-based SPK Capital, an investment firm, has funded San Francisco-based Pipeline Healthcare, Pipeline said last week. Pipeline said SPK Capital led a $2.5M, Series A funding round for the firm. Pipeline Healthcare is a provider of...

San Diego-based Prometheus Laboratories, a developer of specialty pharmaceuticals, and the Regents of the University of California, Los Angeles campus, said Thursday night that they are in a exclusive research agreement. The two said that U...

Culver City-based Sofie Biosciences, a firm developing agents and devices for molecular imaging, said today that it has raised $2M in funding. The round came from Cycad Group and other investors. Sofie Biosciences technology is being applie...

Santa Barbara-based BioIQ, the diagnostic testing and screening service provider headed by Justin Bellante, said Tuesday that it has simplified access to personal health records on the site. The firm--which offers up home test kits and scre...

San Diego-based Awarepoint, a developer of enterprise, real-time location systems for the hospital market, has raised $9M in a financing round, the firm has announced. According to Awarepoint, the funding came from Cardinal Partners, Jafco ...

Monrovia-based Prolacta Bioscience, the venture backed firm which is extracting nutritional fortification from human breast milk, used to help premature and other ill infants, said Wednesday that it has renewed an agreement with the Interna...

San Diego-based Awarepoint, a developer of real-time, asset and patient tracking products for hospitals, said today that it has named Jay Deady as the company's new President and CEO. Deady was most recently EVP of Client Solutions for Ecli...

San Diego-based Histogen, a developer of regenerative medicine products, announced today that it has raised $10M in a Series A financing round. The financing came from private investors, including Secure Medical, Leonard Lavin, Lordship Ven...

Los Angeles-based Total Immersion, the developer of augmented reality software tools, reports today that it has added Los Angeles-based Vantage Surgical Systems as a partner. According to Total Immersion, Vantage is looking to use its augme...

San Diego-based Awarepoint, a developer of real time, location monitoring systems for hospitals, has raised another $3.2M in capital, according to a recent regulatory filing by the firm. The filing indicates current investors Venrock, JAFCO...

Thousand Oaks-based Amgen said Thursday that it has received U.S. Food and Drug Admnistration (FDA) approval on its denosumab treatment for reducing fractures and other bone problems in cancer patients. The new drug will be sold under the n...

San Diego-based BeneChill, a firm developing medical devices for treatment of cerebral ischemia, has raised $600,000 as part of $1.2M in debt funding, according to a regulatory filing by the firm this week. Source of the new funding was not...

San Diego-based Aires Pharmaceuticals, a developer of treatments for pulmonary arterial hypertension, said this morning that it has raised $20M in a Series B funding round. The round was led by MPM Capital, and also included prior investor ...

San Diego-based biopharmaceuticals firm Ceregene announced this morning that it has raised $11.5M in a Series D funding round. The round was co-led by Hamilton Bioventures and Alta Partners, and also included MPM Capital and Investor Growth...

San Diego-based Ambit Biosciences, a firm discovering, developing and commercializing targeted small molecule therapeutics for treating cancer, has filed for an IPO, saying it is looking to raise up to $86.25M on the Nasdaq Global Market. T...

San Diego-based Ambit Biosciences, a developer of small molecule treatments for cancer, said today that it has named Faheem Hasnain as its Chairman of the board, added Alan Fuhrman as its Chief Financial Officer, and promoted Chritopher Mor...

Agoura Hills-based Caldera Medical, a developer of medical devices for the gynecology, urology and urogynecology markets, said this week that it has received two grants worth a total of $488,958 from the U.S. Department of the Treasury. Acc...

San Diego-based Zogenix has updated its S-1, saying this morning the firm intends to offer 6 million shares of its common stock on the Nasdaq Global Market as ZGNX. The firm also said it currently estimates the firm's initial offering price...

San Diego-based International Technidyne Corporation (ITC), a provider of blood testing devices, has been acquired by private equity firm Warburg Pincus, and also merged with venture backed San Diego firm Nexus Dx. According to ITC, a subsi...

Irvine-based PathCentral, a provider of pathology services and software to community pathologists, said Tuesday that it has raised $10M in a Series B funding round. The round was led by Okapi Venture Capital, Arboretum Ventures, and Baird V...

Carlsbad-based GenMark Diagnostics, a developer of molecular diagnostic testing systems, said this morning that it has acquired a non-exclusive license to technology from Innogentics. The firm said the licesne covers Innogenetics' Hepatitis...

Irvine-based Endologix, a developer of minimally invasive treatments for aortic disorders, said this morning that it has agreed to acquire Nellix, a developer of medical devices for treating abdominal aortic aneurysms (AAAs). Endologix said...

La Jolla-based Regulus Therapeutics reports today that it has received $10M in an equity investment from drug maker Sanofi-Aventis. The firm said the investment came as part of its strategic alliance with Sanofi-Aventis, which was signed Ju...

San Diego-based Phenomix, a developer of diabetes drugs, has shut down, according to reports. The firm--which was developing drugs to help treat diabetes--apparently has laid off most of its staff, and is looking for a buyer for the assets....

Calabasas-based KYTHERA Biopharmaceuticals said this morning that it has added Francois Kress, the President and CEO of Prada, to its board of directors. KYTHERA, which develops products for the aesthetic medicine market, said that Kress ha...

Los Angeles-based Response Genetics, a developer of molecular diagnostics tests for cancer, said Tuesday that it has lost its Chief Operating Officer, Michael B. McNulty. The reason for McNulty's departure was not announced. The firm said t...

San Diego-based aTyr Pharma, a developer of biotherapeutics aimed at the blood, immune, and metabolism disorder areas, announced today that it has raised $23M in a Series C equity financing round. The round was led by Domain Associates, and...

Aliso Viejo-based Clarient, a developer of cancer diagnostic tools, is being acquired by GE Healthcare in a deal worth $580M. According to GE Healthcare, which is a unit of General Electric, it will pay $5.00 per common share or $20.00 per ...

Laguna Hills-based Minnow Medical, a developer of treatments for peripheral vascular disease therapy, said said Wednesday that it has raised $4.7M in a combination of equity and convertible debt. According to the firm, it sold $3.2M in pref...

Costa Mesa-based CLRS Technology, a developer of personal care products for treating acne, has been acquired. According to acquiring firm Solta Medical, it is acquiring CLRS for the payment of approximately $1.1M of debt, plus potential fut...

The University of Southern California announced Friday, in conjunction with the inauguration of new president C. L. Max Nikias, that Ming Hsieh, the founder of Monrovia-based COgent, has donated $50M to endow a new instute focused on nano-m...

San Diego-based Pathway Genomics, a provider of genetic testing services, has raised additional funding, according to the firm's legal counsel, Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. Amount, details, and source of the new fundi...

San Diego-based Halozyme Therapeutics, a firm developing biopharmaceuticals for the endocrinology, oncology, dermatology and drug delivery markets, said late Monday that it has cut its workforce by approximately 25 percent, as it says it is...

San Diego-based Ligand Pharmaceuticals, a developer of a broad line of pharmaceuticals, said today that it has named Sunil Patel to its board of directors. Patel is Senior Vice President of Corporate Development for OncoMed Pharmaceuticals,...

La Jolla-based Synthetic Genomics and the J. Craig Venter Institute, the nonprofit genetic research organization of genetic sequencing pioneer J. Craig Venter, said today that they have formed a new company in San Diego, Synthetic Genomics ...

San Diego-based Ligand Pharmaceuticals announced today that it has agreed to sell its combinatorial compound library and screening technology, in a deal worth $1.8M. According to Ligand, it is selling the technology to Venenum Biodesign, LL...

Los Angeles-based LivHOME, a venture backed provider of in-home care for seniors, said today that it has launched a franchising program. The firm--which is venture backed by Scale Venture Partners, Tullis Dickerson, and Kilne Hawkes--said t...

Vista-based Opthonix, a developer of wavefront guided, high definition vision eyeglasses, has raised $5.39M as part of an ongoing, $12.1M financing, according to a regulatory filing from the firm earlier this week. Details on the funding ha...

Shareholders of Aliso Viejo-based Valeant Pharmaceuticals and Canadian firm Biovail have approved Valeant's acquisition by Biovail, despite objections from Biovail founder Eugene Melnyk and a a number of California state lawmakers. The deal...

Santa Barbara-based QAD, the developer of enterprise resource planning software, said this morning that San Diego-based life sciences firm Nexus Dx has adopted its software. According to QAD, Nexus Dx is using QAD Enterprise Applications, i...

San Diego-based Cylene Pharmaceuticals reported today that it has raised $12M in a financing round, from its existing investors, as it kicks off a Phase I clinical trial. The developer of treatments for multiple myeloma said the funding cam...

Santa Barbara-based CytomX Therapeutics, a biotechnology firm developing antibodies, said this morning that it has raised $30M in a Series B funding round. The round was led by Third Rock Ventures, and also included the Roche Venture Fund. ...

San Diego-based A-Life Medical, a firm which developed software to help physicians to properly code the billing of medical procedures, has been acquired by a unit of UnitedHealth Group, the firms said Tuesday. According to Ingenix, the Unit...

Aliso Viejo-based Valeant Pharmaceuticals, the specialty pharmaceuticals firm that is in the midst of a merger with Biovail, said today that it is planning a one time, special cash dividend of $16.77 per share, in conjunction with the merge...

Yesterday, there were a lots of startups who launched at the DEMO Fall event in Silicon Valley. One of the local firms that launched was Los Angeles-based Health In Reach (www.healthinreach.com). HealthInReach was founded by Scott Sangste...

Los Angeles-based Health In Reach, a new startup founded by Scott Sangster, has launched its new service today at the DEMO Fall conference. Health In Reach is focused on helping patients find doctors, schedule appointments, and receive upfr...

Irvine-based Kareo, a developer of web-based medical billing software, announced today that it has raised $9.5M in an investment round. According to Kareo, the funding came from OpenView Venture Partners. The firm said the new funding will ...

Aliso Viejo-based Valeant Pharmaceuticals is planning deeper cuts, after the firm's merger with Biovail, according to an email released by the firm via a regulatory filing Tuesday. According to Valeant, it now expects to cut 25 percent of i...

Poway-based NEXUS Biosystems, a developer of automated sample management systems for the pharmaceuticals and biotech industry, said today that it has completed its acquisition of REMP AG of Switzerland, a developer of sample management syst...

San Diego-based Zogenix, a developer of needle-free, delivery systems for the treatment of acute migraines and cluster headaches, has filed for a $90M IPO. The IPO is being underwritten by Wells Fargo Securities, Leerink Swann, Oppenheimer ...

San Diego-based pharmaceuticals firm Somaxon Pharmaceuticals reports this morning that it is now in commercial availability of its Silenor compound in the United States. The firm said it has now implemented wholesale and retail stocking of ...

San Diego-based Accumetrics, a developer of medical devices used to measure antiplatelet therapy, a technique used to prevent heart attack and stroke, said this morning that it has closed on a $24M funding round. The firm said the funding c...

La Jolla-based Cebix, a developer of treatments for type 1 diabetic neuropathy, has raised $14.0M in a new funding round, according to a regulatory filing by the firm today. Details on the funding have not been announced by the company, how...

San Diego-based DexCom, a developer of continuous glucose monitoring systems, said Monday afternoon that Donald A. Lucas has resigned from the firm's board of directors. Lucas is Founding Managing Member at RWI Group, which was an investor ...

San Diego-based Otonomy, a biopharmaceuticals firm developing products to treat disorders of the inner and middle ear, announced today that it has raised $38.5M in a Series B financing. The round was led by Novo Ventures and RiverVest Ventu...

San Diego-based venture capital firm Finistere Ventures, which is focused on early stage medical devices and biotechnology investments, is in the midst of raising a new fund, Finistere Ventures II, according to VentureWire this week. No oth...

Looking to capitalize on the firm's customer demographics, San Diego-based GreatCall, the operator of the Jitterbug easy-to-use cell phone, said today that it has rolled out a new "Medication Reminder" service. The company, which is venture...

San Diego-based venture capital firm Enterprise Partners is one of the firms in a $39M, Series E funding round for Mountain View-based Complete Genomics, Complete Genomics said today. The round was led by Sands Capital, and also included Es...

Carlsbad-based Life Technologies, a developer of DNA sequencing technology, said Tuesday afternoon that it has agreed to buy Ion Torrent in a $375M deal. According to the firm, the cash and stock deal also includes up to $350M in additional...

San Diego-based Cibus Global, a developer of technology for engineering agricultural crops, has raised $1.16M in funding, according to a regulatory filing by the firm Tuesday. The funding appears to be part of an ongoing, $2.6M fundraising ...

San Diego-based REVA Medical, a developer of stents used for treating coronary artery disease, has filed for an IPO in Australia. According to REVA, it is looking to raise up to $63M in an offering on the Australian Securities Exchange. REV...

Tustin-based Toshiba America Medical Systems, the marketing, distribution, and services arm of Toshiba's diagnostic imaging systems group, said today that it has named Stuart Clarkson as Director of its MR Business Unit. Toshiba said Clarks...

San Diego-based CareFusion, a manufacturer of medical devices including pumps, patient identification systems, ventilators, surgical instruments, and more, said last night that it is cutting 700 jobs in a company-wide restructuring. The fir...

Westlake Village-based Aspyra said Monday that it has been acquired by Orion Healthcare Ventures LLC. The firm, which develops healthcare information technology products, did not disclose financial details of the acquisition. Orion Healthca...

San Diego-based MabVax Therapeutics, a biotechnology firm focused on vaccine and antibody therapies for treating cancer, said today that it has received a $1.1M, Phase 2 Small Business Technology Transfer Program Award (STTR) from the Natio...

San Diego-based XIFIN, a developer of revenue cycle management software-as-a-service for the healthcare industry, said Monday that it has named Craig Kussman as Chief Financial Officer at the firm. Kussman has previously served at Breach Se...

Carslbad-based Life Technologies, a developer of genomic analysis technology, and the University of California at San Diego's Moores Cancer Center, said this morning that the two are collaborating on a research effort. According to the two,...

San Diego-based Concerro, a developer of hospital workforce management software, said Tuesday that it has named Cindy Watson as Chief Operating Officer of the firm. Watson was most recently Vice President of Client Services for the firm. W...

San Diego-based Althea Technologies, a provider of contract development and manufacturing for the life sciences market, has raised $17M in debt funding, according to financing provider Hercules Technology Growth Capital. Use for the funding...

San Diego-based Trius Therapeutics is set to hit the markets today, after pricing its IPO last night. Trius will trade on the NASDAQ Global Market under the symbol TSRX. Trius, a biopharmaceuticals firm developing antibiotics, priced its IP...

San Diego-based Trius Therapautics has slashed its IPO offering price, saying today in a filing with the SEC that it will offer 10,000,000 shares of its common stock at $5.00 per share. The firm, which will list on the Nasdaq Global Market ...

San Diego-based Conatus Pharmaceuticals said Friday that it has acquired the Idun Pharmaceuticals subsidiary of Pfizer. Financial terms of the buy were not disclosed. According to Conatus Pharmaceuticals, it is focused on developing drugs f...

San Diego-based Illumina said today it has launched a new, real-time PCR system for the genetic analysis market, and also revealed that it acquired Carlsbad-based Helixis, a developer of those real-time PCR systems. The deal was worth $70M ...

Santa Barbara-based BioIQ, the provider of online wellness testing and related services for employees and their employers, has upped its latest round of funding to just over $1.0M, according to a regulatory filing from the firm today. Detai...

Thousand Oaks-based biotech giant Amgen said Thursday that it has named Ronald D. Sugar to the firm's board of directors. Sugar is the former Chairman of Northrop Grumman Corp, having served as Chairman and CEO of the defense firm from 2003...

Poway-based NEXUS Biosystems, a developer of automated sample management systems for the biopharmaceuticals industry, said Thursday that it has signed an agreement to acquire REMP AG, a Swiss-based firm which provides sample management syst...

Thousand Oaks-based biotech giant Amgen announced this morning that it has appointed Jonathan M. Peacock as Chief Financial Officer. Peacock replaces Michael A. Kelly, who has been acting CFO since May. According to Amgen, Peacock joins fro...

San Diego-based Illumina announced this morning that it has appointed Melina Cimler as Vp Quality and Regulatory Affairs. Cimler joins the firm from PandiaDx Consulting, and has also served at Beckman Coulter, Abbot Molecular, and Gen-Probe...

San Diego-based Zogenix announced today that it has just raised $35M in debt, and $15M in equity funding. The developer of biopharmaceuticals said that the $35M in debt came from Oxford Finance Corporation and Silicon Valley Bank, and was s...

Santa Ana-based Irvine Scientific, a developer of medical devices for the cell culture and biopharmaceutical industry, said this morning that it has opened up a second facility, in Tokyo, Japan. The firm said the new facility will manufactu...

Thousand Oaks-based Ceres, a developer of biofuels crop technology, said Thursday that it has completed a private offering of convertible preferred stock. The funding came from Artal Luxembourg, Ambergate Trust, Gimv, and other undisclosed ...

Seattle- and Irvine-based Uptake Medical, a developer of medical technologies for the treatment of lung disease, said today that it has completed a Series B financing round worth $17.5M. Uptake said the round was led by Maverick Capital, an...

San Diego-based Illumina, a developer of life sciences tools and sequencers, said this morning that it has named Gerald Moller, Ph.D., to its board. Moller is an advisor at investment firm HBM Bio Ventures AG. Moller has previously served a...

Aliso Viejo-based LenSx Lasers, a developer of laser technology used for cataract surgery, has been acquired by Alcon, Alcon said late Tuesday. According to Alcon, it will pay $361.5M in cash for LenSx shareholders, plus up to $382.5M in co...

San Diego-based Illumina announced this morning that it has named Nicholas J. Naclerio, Ph.D., as Senior Vice President, Corporate Development at the firm. Naclerio was the co-founder and executive chairman of Quanterix, and also has served...

San Diego-based TargeGen, a firm developing small molecule kinase inhibitors for the treatment of myelofibrosis (MF) and polycythemia vera (PV), has been acquired by Sanofi-aventis, in a deal worth as much as $560M, the firm said Wednesday....

Los Angeles-based Abraxis BioScience, a developer of cancer treatments, is being acquired by Celegene Corporation in a deal worth $2.9 billion. According to Celegene, it will pay $58.00 in cash and 0.2617 shares of its common stock for Abra...

Irvine-based AqueSys, a developer of medical devices for the treatment of glaucoma, said today that it has raised $35M in a Series C funding round. The round was led by Longitude Capital and Rho Ventures, and also included Accuitive Medical...

Monrovia-based Xencor, the biopharmaceuticals firm headed by Dr. Bassil Dahiyat, has inked a licensing deal with German pharmaceuticals firm MorphoSys, Morphosys said over the weekend. Accordin to MorphoSys, it has gained an worldwide licen...

San Diego-based Nereus Pharmaceuticals, a firm developing drugs for the treatment of lung cancer, said Tuesday that it has raised another $20M in funding and commitments from its venture backers. The new funding round was led by HBM Biovent...

Irvine-based Spectrum Pharmaceuticals, a biopharmaceuticals firm focused on oncology and hematology, said today that it has named James E. Shields as its Chief Commercial Officer. Shields was most recently with Teva Pharmaceuticals Industri...

San Diego-based DexCom, a developer of continuous glucose monitoring systems, said today that it has named Steven R. Pacelli as its Chief Operating Officer, and Jorge Valdes as Chief Technology Officer. Pacelli has been Chief Administrative...

Aliso Viejo-based pharmaceuticals firm Valeant said today that it has agree to merge with Biovail, a Toronto-based pharmaceuticals developer. According to the firms, the deal calls for Valeant stockholders to receive $16.77 in cash per shar...

San Diego-based scientific instruments maker Gen-Probe has invested $50M in a Northern California firm developing DNA sequencing technology, Pacific Biosciences. According to the two firms, Gen-Probe made the investment as part of a larger ...

San Diego-based Cyntellect, a life sciences firm developing stem cell and other biopharmaceuticals products, said today that it has named Saiid Zarrabian as the firm's CEO. Zarrabian replaces Fred Koller, who becomes Chief Technology Office...

Monrovia, California-based Prolacta Bioscience, the venture backed firm developing human milk fortifiers for premature infants, announced this morning that it will be donating funds to the Susan G. Komen for the Cure as part of its milk don...

San Diego-based Cytori Therapeutics, a developer of medical devices and instruments for the cosmetic and reconstructive surgery market, announced today that it has received $20M in a loan facility. The facility came from GE Capital, Healthc...

Santa Ana-based MP Biomedicals, a diversified manufacturer of life sciences products, said this morning that it has signed a definitive agreement to acquire New Zealand firm ICPbio International LTD, in an asset deal. ICPbio is a manufactur...

Irvine-based AqueSys, a medical device firm which is working on a proprietary surgical device for the treatment of glaucoma, has raised $7.5M of a $35M funding round, according to a regulatory filing by the firm today. Source of the new fun...

San Diego-based Otonomy, which is developing treatments for Meniere's disease, said today that it has raised $10M in a Series A financing round. The round came from Avalon Ventures. According to Otonomy, the funding will go towards supporti...

San Diego-based Otonomy, a biopharmaceuticals firm developing drug therapies to treat inner and middle ear disorders, has raised $10.56M as part of an ongoing, $26.0M fundraising effort, according to a regulatory filing by the firm. Source...

A Seattle-area firm, Kineta, with ties to two University of California, Irvine professors has scored funding support from the Iacocca Family Foundation, created by Lee A. Iacocca, the company said today. Kineta said that the Iacocca Family ...

San Diego-based Arena Pharmaceuticals, a firm developing biopharmaceuticals, including a compound targeted at weight loss and weight management, said today that it is raising $35.5M in an equity investment from Deerfield Management. Publicl...

Carlsbad-based Life Technologies said Wednesday that it has made an equity investment in Synthetic Genomics, a firm commercializing synthetic genomic advances. Terms of the investment were not announced. Synthetic Genomics develops technol...

Thousand Oaks-based Amgen said Tuesday evening that it has received U.S. Food and Drug Administration (FDA) approval on its pRolia treatment of osteoporosis for postmenopausal women. The firm said the approval was based on its Phase 3 study...

San Clemente-based Altura Medical announced this morning that it has raised $20M in a Series A financing round. The firm said the funding was led by New Leaf Venture Partners, and also included Advanced Technology Ventures and SV Life Scien...

Carlsbad-based Life Technologies announced this morning that it has acquired a majority stake in Geneart AG, a synthetic biology company. The firm said it now owns approximately 74 percent of Geneart, after purchasing approximately 554,000 ...

Pasadena-based Genmark Diagnostics, a maker of molecular diagnostics equipment, lowered its initial public offering price to between $6.00 and $7.00 per share yesterday, down from an earlier anticipated initial public offering price of betw...

Aliso Viejo-based Valeant Pharmaceuticals said today that it has completed its acquisition of Aton Pharma, a specialty pharmaceuticals firm focused on ophthalmology and other drugs. The deal was worth $318M. Aton Pharma was based in lawrenc...

Lake Forest-based ReVision Optics, a firm developing implantable lenses for correcting vision, announced Tuesday that it has raised $35M. The round was led by ProQuest Investments, and also included Domain Associates, Canaan Partners, and I...

Lake Forest-based ReVision Optics, a developer of implantable lenses for treating presbyopia, has received $35.0M in a new round of venture funding, according to a regulatory filing by the firm Tuesday. Details on the funding have not yet b...

San Diego-based CareFusion, a provider of medical devices, said Monday that it has completed its $225M cash acquisition of Medegen, a developer of needleless access connectors for delivering intravenous medication to patients. The acquisiti...

San Diego-based Halozyme Therapeutics said over the weekend that it has delivered notice to Baxter Healthcare, that Baxter is in breach due to failure to provide its HYLENEX (hyaluronidase human injection) product per the firm's development...

Aliso Viejo-based Enclarity, a developer of healthcare information solutions, recently received an investment from Nashville, Tennessee-based Emdeon. Financial terms of the investment were not announced, however, Emdeon said that the minori...

Aliso Viejo-based Sequent Medical, a firm focused on medical devices for treating neurovascular disease, said Thursday that it has raised $15.6M in a Series B funding round. The funding was led by Domain Associates, and also included Versan...

San Diego-based Astute Medical, a developer of biomarker-based medical diagnostics products, has raised $26.5M in a Series B funding round, the firm said yesterday. The round was co-led by Domain Associates and Delphi Ventures. According to...

Santa Monica-based LIVESTRONG.COM, the online health information site run by Demand Media and the Lance Armstrong Foundation, said today that it has named Dr. Leslie Anne Saxon as its Chief Medical Advisor. Saxon is Professor of Medicine, C...

Los Angeles-based Canon Communications, a publisher and trade show operator serving the pharmaceutical industry, said Monday that it has acquired Pharmalot, a blog focused on news and information in the pharmaceutical industry. Financial te...

San Diego-based ADVENTRX Pharmaceuticals, a publicly held developer of cancer treatments, said today that it is in a private placement where it will receive $19.2M in a Series F convertible preferred stock round. Source of the new funding w...

Santa Barbara-based InTouch Technologies, a developer of remote presence systems used for the healthcare industry, announced today that it has raised $10M in a private placement. The round came from Beringea, via its InvestMichigan! Growth ...

San Diego-based Althea Technologies, a contract development and manufacturing firm for the biopharmaceuticals industry, said today that it has acquired the assets and IP portfolio of Altus Pharmaceuticals. Financial terms of the deal were n...

San Diego-based Illumina, a developer of gene sequencing tools, said today that it has named Elizabeth Brady as the firm's Vice President, Global Supply Chain, and Emily S. Winn-Deen, Ph.D., as its Vice President, Diagnostics Development. B...

Schrodinger, a firm focused on computational drug design for the pharmaceuticals and biotechnology research industry, announced today that Bill Gates--through his investment firm, Cascade Investment--has invested in the company. The firm, w...

Thousand Oaks-based Amgen announced this morning that it has named Robert A. Bradway as the firm's President and Chief Operating Officer. Bradway has been at Amgen since 2006, and was most recently Executive Vice President and Chief Financi...

Los Angeles-based Kythera Biopharmaceuticals, which is developing aesthetic medicine products, said today that it has named Pierre J.G. Corin as the firm's Vice President, Global Clinical Operations. Corin joins the firm from Allergan Medic...

San Diego-based Aragon Pharmaceuticals, a developer of treatments for hormonally driven cancers, said today that it has raised $22M in a Series B funding. The funding came from Aisling Capital, OrbiMed Advisors, and the Column Group. As par...

Aliso Viejo-based Valeant Pharmaceuticals announced today that it has entered into a binding agreement to acquire a pharmaceuticals firm located in Brazil, in a deal worth approximately $56M (97 million Brazilian reals). According to Valean...

Laguna Hills-based CardioPolymers, a developer of an implantable device for treating congestive heart failure, has added $1.35M to its venture funding, according to numbers from the latest PricewaterhouseCoopers/NVCA quarterly venture capit...

San Diego-based Sotera Wireless, a developer of patient monitoring technology, announced Monday afternoon that it has raised $10.75M in a strategic investment round. The round was led by West Family Holdings, LLC, and also included prior in...

San Diego-based AltheaDx, a developer of molecular diagnostics products, has raised $6M in a Series A round, the firm revealed today. The firm said the round was led by Telegraph Hill Partners. AltheaDx is focused on developing diagnostic t...

San Diego-based Sotera Wireless, a developer of wireless vital signs management product, has raised $10.7M as part of an ongoing, $15.0M funding round, accoridng to a regulatory filing today. Source of the new funding was not disclosed. The...

San Diego-based Amplyx Pharmaceuticals announced Thursday that the firm has raised $1.5M in a Series A funding round. According to the firm, the round came from Golden Seeds, a nationwide angel group investing in women-led companies, with p...

San Diego-based NexMed, a specialty contract research organization, announced earlier this week that it has named Terry Ladd as Vice President of Business Development at its Bio-Quant subsidiary, and Richard Martin as Vice President of Chem...

San Diego-based Fate Therapeutics, a developer of stem cell therapeutics, announced this morning that it is in a definitive agreement to acquire Canadian biotechnology firm Verio Therapeutics. Financial terms of the acquisition were not dis...

San Diego-based Accelerys and Santa Clara-based Symyx announced this morning that the two are in a all-stock merger to create a new, scientific information software firm. The firms said that Symyx shareholders will receive 0.7802 shares of ...

San Diego-based CareFusion, a firm that develops a wide range of medical devices, said today that it is paying $225M in cash for Ontario, California-based Medegen. Medegen develops needleless access valves and disposable IV sets that are us...

Irvine-based Reverse Medical Corporation, a developer of microcatheters for treating neurovascular disorders, announced today that it has raised $14M in a Series B funding round. The firm said that the new funding came from Wexford Capital,...

Westlake Village-based Cynvenio Biosystems announed this morning that the firm has appointed two new VPs. According to Cynvenio, it has added David J. Sauvageau as the firm's Vice President, Engineering and Product Development, and Dr. Paul...

Los Angeles-based Response Genetics, a firm developing molecular diagnostic tests for cancer, announced this morning that its Chief Financial Officer, Thomas Stankovich, has resigned. The firm said that Stankovich resigned to "pursue other ...

San Diego-based Cyntellect, a developer of cytometry equipment, has raised $3.0M in a new funding round, according to a regulatory filing from the firm earlier this week. Details on the funding have not been disclosed by the company. Cyntel...

San Diego-based Genomatica, a developer of chemical processes based on bio-manufacturing, has raised $15M in a Series C funding round, the firm announced today. According to the firm, the new funding was led by TPG Biotech, and also include...

Vista-based Gc-Free, a firm developing diagnostic tools to predict risks of colon, prostate, breast and other cancers, has raised $700,000 in an equity funding, according to a regulatory filing by the firm today. Source of the funding was n...

San Diego-based Elecelyx Therapeutics, a stealth mode biotech firm, has raised $1.2M in a funding round, which includes Morgenthaler Ventures, according to a regulatory filing this week. Details on the funding have not been announced by the...

Aliso Viejo-based Valeant Pharmaceuticals announced today that it is in an agreement to buy a Brazilian manufaturer of branded, generic and over the counter pharmaceuticals. According to Valeant, the deal is worth approximately $28M. Valean...

Pasadena-based Genmark Diagnostics, a developer of a diagnostic biomarker detection system, has filed for an IPO, saying it is looking to raised up to $46.0M in an IPO on the NASDAQ Global Market. The firm said it is looking to trade as GNM...

Carlsbad-based Isis Pharmaceuticals, a firm developing antisense drugs for treating cardiovascular, metabolic and severe neurodegenerative diseases, and cancer, said this morning it has earned $6M in a milestone payment from Bristol-Myers S...

Oxford, England-based Enigma Diagnostics, a molecular diagnostics firm, said today that it has opened up a new, regional headquarters in San Diego. Enigma said the new, 17,000 sq. ft. office is in the Sorrento Valley, where it will house sa...

San Diego-based La Jolla Pharmaceuticals, the failed biopharmaceuticals firm which was previously developing treating lupus renal disease, reported today that it has received notification from the Nasdaq that it will be delisted from the ma...

Aliso Viejo-based Valeant Pharmaceuticals said today that it has entered into an agreement with Spear Pharmaceuticals, where the firm will commercialize a cream used to reduce wrinkles and fade irregular pigmentation due to sun damage. Vale...

San Diego-based Trius Therapeutics, which is looking to IPO on the Nasdaq as TSRX, indicated in a filing today that it is looking to price its IPO at between $12.00 and $14.00 per share. The firm's IPO is being underwritten by Credit Suiss...

Tustin-based Toshiba America Medical Systems, a manufacturer of diagnostic imaging systems for the healthcare market, said today that it has named Doug Ryan as Vice President, Marketing and Strategic Development, heading up the firm's strat...

San Diego-based Quidel, a developer of medical diagnostic tests, said Friday that it has completed its $130M acquisition of Diagnostic Hybrids. Diagnostic Hybrids was located in Athens, Ohio, and develops in-vitro diagnostic assays used by ...

San Diego-based TriTech Software Systems, a developer of public safety and other software for law enforcement, fire and emergency management services agencies, said Thursday that it has entered into an agreement to acquire Ortivus North Ame...

San Diego-based Tioga Pharmaceuticals said today that it has raised $18M in a new equity funding. The funding came from Forward Ventures, New Leaf Venture Partners, BB Biotech Ventures, and Genesys Capital Partners. According to Tioga, the ...

San Diego-based NexMed, a clinical research organization focused on in vitro and in vivo pharmacology services, said earlier this week that it raised $2.3M in a private placement. Name of the investors were not disclosed. The firm said the ...

Irvine-based Quality Systems, which develops healthcare information systems, said today that it is in an agreement to acquire Opus Healthcare Solutions, a provider of web-based, clinical information systems. Financial details of the buy wer...

The UCLA School of Public Health is looking to tap into the power of social networks, in an attempt to encourage adolescents from 13 to 17 to take better care of their health. According to health care insurer Health Net and UCLA, the two ar...

Monrovia-based Xencor, a developer of antibody discovery technology, said this morning that it has named Edgardo Baracchini, Ph.D., as Chief Business Officer at the company. Baracchini joins the firm from Metabasis Therapeutics, where he wa...

San Diego-based PatientSafe Solutions, a developer of software and bar code systems used for management of patient and workflow management in hospitals, has reported raised $30M in a new round of funding. The funding was first reported by V...

Laguna Beach-based OrthAlign, a developer of medical devices for computer assisted surgery, has raised $5.16M in a Series A-2 funding round. Source of the funding was not announced by the firm, however, the firm has previously raised capita...

San Diego-based Tragara Pharmaceuticals, a developer of biopharmaceuticals aimed at cancer and inflammation treatments, has raised another $5M in a funding round, according to a regulatory filing by the firm last week. The filing indicates...

Carlsbad-based Life Technologies, a manufacturer of scientific equipment to the life sciences industry, has completed its sale of its mass spectrometry business to Danaher in a deal worth $450M in cash, the firm announced this morning. The...

Los Angeles-based Abraxis BioScience confirmed this morning that it is still planning on a spinoff of its Abraxis Health division this year, and has named a number of executives as part of the effort. According to Abraxis, it has named Bruc...

Irvine-based Neomend, a developer of sealants for the surgical market, announced this morning that it has raised $30M in a Series D funding round. Neomend said the round was led by Clarus Ventures, which contributed $17M of the total round....

San Diego-based Elevation Pharmaceuticals, a biopharmaceuticals firm developing treatments for repiratory diseases, said Thursday that it has closed on $30M of Series A funding. The funding came from Canaan Partners, TPG Growth, Care Capita...

Valencia-based U.S. HealthWorks, an operator of occupational health care centers, said today that it has raised $175M in a combination of debt and equity. The firm said the funding will go towards its growth and acquisition strategy. The fu...

Thousand Oaks-based Amgen said Thursday that it is donating $2M to Haiti relief efforts, as well as encourage its staff to contribute their own funds to organizations aiding in relief and rebuilding efforts in the country. According to Amge...

Pasadena-based Aliva Pharmaceuticals, a firm developing animal systems for predicting human drug profiles, has raised $12.87M in funding, according to a recent regulatory filing by the firm. Source of the new funding was not disclosed. Acco...

Irvine-based SEDLine said today that it has acquired Hospira's brain function monitoring business, and scored an equity investment from Masimo. Financial details of the acquisition were not disclosed by the firm. According to SEDline, the f...

San Diego-based biopharmaceuticals firm VentiRx Pharmaceuticals said today that the firm has raised $25M in a Series A extension round. The firm, which is developing treatments for cancer, respiratory, and inflammatory disease, said the rou...

Westlake Village-based Cynvenio Biosystems, a developer of high speed, bioseparation instruments for the life sciences market, has raised $1.96M in a Series B funding round, according to a regulatory filing by the firm today. Source of the ...

Laguna Beach-based Advanced Cardiac Therapeutics, which develops advanced cardiac ablation systems, said this morning that it has raised $5M in a Series B funding. According to the firm, the funding was led by NBGI Ventures. The firm said t...

San Diego-based Tandem Diabetes, a developer of insulin pumps, has raised another $31.0M in funding, bring its current funding round to $52.3M, according to a regulatory filing by the firm lsat week. Source of the new funding was not disclo...

Los Angeles-based Zynx Health, a provider of clinical decision support systems for the healthcare industry, announced this morning that it has tied with IT healthcare provider MEDITECH, to offer a package addressing the American Recovery an...

San Diego-based Quidel, a developer of diagnostic tests, said today that it is in a definitive agreement to acquired Diagnostic Hybrids, a manufacturer of in-vitro diagnostic assays, in a deal worth approximately $130M in cash. According to...

San Diego-based Inovio Biomedical said this week that it has tapped a Merck veteran for its new Chief Medical Officer. According to Inovio, it has hired on mark L. Bagarazzi, M.D>, as Chief Medical Officer heading up worldwide clinical deve...

San Diego-based Traversa Therapeutics, a biopharmaceuticals firm developing RNA interference (RNAi) technology, said earlier this week that it has named Curt W. Bradshaw as Vice President of Research and Development. Bradshaw joins the firm...

Los Angeles-based private equity firm Marlin Equity Partners has acquired Pennsylvania-based Liquent, a developer of software and services for the life sciences industry, from Thomson Reuters. Financial details of the deal were not disclose...

Cypress-based Christie Digital Systems, a developer of digital display systems, said Wednesday morning that it has acquired substantially all of the assets of Luminetx, a developer of medical devices used for detecting and mapping veins in ...

San Diego-based Ambit Biosciences inked a deal Friday with Astellas Pharma Inc., where Astellas will pay the firm $40M in cash, and up to $350M in pre-commercialization milestones, in a joint partnership to develop and commercialize Ambit's...

Monrovia-based Xencor, a developer of antibody engineering technology, reported today that the firm has received a milestone payment from Pfizer, as part of the firm's antibody technology license agreement with Pfizer. Amount of the payment...

Thousand Oaks-based Amgen and Colorado-based Array BioPharma announced Monday evening that Amgen is licensing the exclusive worldwide rights to Array's compounds for treating Type 2 diabetes, in a deal worth $60M plus additional contingent ...

San Diego-based Calixa Therapeutics, a biopharmaceuticals firm developing antibiotics to treat multi-drug resistant organisms, has been acquired by Cubist Pharmaceuticals, a Massachusetts-based biotherapeutics firm. The deal was worth $92.5...

San Diego-based Pfenix, a new startup focused on biotechnology technology for producing proteins, has spun out of Dow Chemical Company, Pfenex said this week. As part of the spinout, the firm has received $24M in a Series A funding round. T...

San Diego-based EVOFEM, a firm developing feminine hygiene products, said today that it has raised $25M in a private equity investment. Name of the investor was not disclosed. EVOFEM--which was formerly known as Instead Healthcare--is devel...

San Diego-based Zogenix, a pharmaceuticals firm developing neuroscience disorders and pain treatments, said Monday that it has closed on $35M in a second tranche of Series B funding, bringing the firm's Series B to a total of $71M. The firm...

Poway-based NEXUS Biosystems, a developer of automated sample management systems for the biotech industry, announced this morning that it has acquired Carlsbad-based Aurora Biotechnologies, a developer of microplate products used for sample...

San Diego-based Somaxon Pharmaceuticals, a developer of a drug for the treatment of insomnia, reported this morning that it has received a response from the U.S. Food and Drug Administration on its NAD for Silenor, the firm's treatment of i...

Monrovia-based Xencor, a developer of biotherapeutics, said today that it has named Bruce Carter, Ph.D., most recently the Chief Executive Officer of ZymoGenetics, as Chairman of the firm's board of directors. Carter has also served as Corp...

La Jolla-based Salk Institute for Biological Studies, known for its life science research, disclosed this morning that the firm has added venture capitalists Fred Dotzler to its board of trustees. The institute said that Dotzler, co-founder...

Monrovia-based Xencor, a developer of biotherapeutics technology to improve antibodies, said this morning that it has licensed its Fc engineering technology to Centocor Research & Development, Inc. Financial details of the license were not ...

San Diego-based NextImage Medical, a provider of radiology services to the worker's comp market, said Tuesday that it has raised $5M in a Series A funding round. The round was led by Chrysalis Ventures. NextImage said the funding will go to...

La Jolla-based Fate Therapeutics is reporting this morning that it has raised $30M in a Series B financing round. The firm, which develops stem cell therapies, said the funding was led by OVP Venture Partners, and included Astellas Venture ...

San Diego-based Cyntellect, a developer of products for the biotech industry, has raised $15.5M, according to a regulatory filing from the firm this week. The funding is part of an ongoing, $18.6M fundraising effort, and includes both equit...

San Diego-based Altair Therapeutics said Wednesday afternoon that it has raised $17M in a financing round. According to the firm, the round was led by Domain Associates, and also included AgeChem Venture Fund; Thomas, McNerney & Partners; F...

Carlsbad-based Life Technologies said today that it has signed a definitive agreement to acquire BioTrove, a developer of a high throughput gene expression and genotyping analysis system. Financial details of the acquisition were not disclo...

Valencia-based Advanced Bionics, a manufacturer of cochlear implants, said Monday that it has entered into a definitive merger agreement with Sonova Holdings AG. Financial details of the acquisition were not announced. According to Advance...

San Diego-based Trius Therapeutics has filed for an IPO, saying Friday that it is looking to raise $86.25M in an offering on the Nasdaq Global Market. According to the firm's filing, it has applied to trade under the symbol TSRX. The IPO is...

Los Angeles-based Abraxis Health, the personalized healthcare division of Abraxis BioScience, said this morning that it is expanding in Arizona, and will open up a new biopharmaceuticals manufacturing plant in Phoenix. Abraxis said the plan...

Irvine-based Accenx Technologies, a provider of health information exchange software, has been acquired by Initiate Systems, a data management firm based in Chicago. Financial terms of the deal were not released. According to Initiate, the ...

Thousand Oaks-based biotech giant Amgen is the subject of a lawsuit being filed by New York Attorney General Andrew M. Cuomo, along with 14 other states, claiming that the biotech firm created a kickback scheme to boost drug sales. Accordin...

Carlsbad-based Verdezyne, which is developing technology to improve the fermentation process for biofuels, has raised $2.96M as part of a funding round, according to a regulatory filing from the firm Thursday afternoon. According to the fil...

Patrick Soon-Shiong, the billionaire founder of Abraxis Bioscience, has committed $100M in underwriting guarantees to reopen Martin Luther King, Jr. hospital (MLK), his foundation announced this week. According to the Chan Soon-Shiong Famil...

Del Mar-based One Recovery, an online community site providing support for people recovering from addiction, has raised $1.49M in a funding round, according to a filing from the firm this week. According to the filing, the funding comes as ...

Carlsbad-based Helixis, a developer of nucleic acid analysis tools, has upped its recent funding round to $7.3M, according to a filing from the firm this week. The funding is a continuation of a $10.0M venture round which the firm has been ...

Westlake Village-based Aspyra said Tuesday afternoon that the firm is voluntarily delisting its common stock from the AMEX. The firm, which is listed at APY, said it intends to deslist due to limited trading in its common stock, the costs o...

San Diego-based biopharmaceuticals firms Ligand Pharmaceuticals and Metabasis Therapeutics announced this morning that Ligand is acquiring Metabasis, in a deal worth $3.2M in cash plus rights to receive payments from any royalties or licens...

Thousand Oaks-based Ceres, a developer of energy crops for the biofuels energy, has landed $4,989,144 in a grant from the Department of Energy, as part of a $151M effort to fund energy breakthroughs. According to the DOE, the funding--part ...

Irvine-based Allergan is reporting this morning that it has won a patent infringement case against Exela PharmSci, Inc., Exela PharmSci Pvt., Ltd., Apotex, Inc. and Apotex Corp. in the US District Court for the District of Delaware. Allerga...

Calabasas-based Kythera Biopharmaceuticals, a developer of aesthetic medicine products, has added $10M more in new funding. The new funding came to light in this week's PricewaterhouseCoopers/NVCA MoneyTree report. No details on the funding...

Torrance-based Pathology Inc., a provider of pathology and molecular diagnostics services, has scored both a term loan and revolving line of credit from ORIX Venture Finance, ORIX said Wednesday. Terms and amount of the funding were not dis...

The physical assets of Lake Forest-based Orqis Medical, a venture backed firm which was developing treatments for congestive heart failure, are slated to go up for auction next week, according to auctioneer CowanAlexander. According to Cowa...

Irvine-based U.S. Dermatology Medical Management, a provider of healthcare services for skin cancer treatment and other dermatological conditions, has scored an investment from Los Angeles-based Vicente Capital Partners, Vicente said today....

Aliso Viejo-based Vertos Medical, a developer of medical devices for treating lumbar spinal stenosis, announced this morning that it has raised $15.5M in a Series D funding. The round was led by new investor ONSET Ventures, with participati...

The Food and Drug Adminstration has delayed an approval of Thousand Oaks-based Amgen's osteoporosis denosumab, the firm said Monday, in order to seek more information. According to Amgen, the FDA has requested that the firm include further ...

Carlsbad-based Veredezyne--which was formerly known as CODA Genomics--said today that it has received a $1.7M grant from the National Institute of Allergy And Infectious Diseases (NIAID). The firm said the grant, which lasts for 1.5 years, ...

San Diego-based Gen-Probe said Tuesday that it has signed a definitive agreement to acquire Prodesse, a provider of molecular testing for influenza and other infection diseases. The deal is worth $60M in cash, with provision to increase the...

San Diego-based Cyntellect, a developer of scientific equipment for the life science and stem cell research market, reported today that it has opened up a new European headquarters in the U.K. The firm said the firm now has a team of sales,...

San Diego-based Accumetrics said today that it has raised $16.5M in new capital. The funding round came from Arnerich Massena, BBT Fund/Apothecary Capital, Essex Woodlands Health Ventures, Kaiser Permanente Ventures and RiverVest Venture Pa...

San Diego-based Nexus DX, a stealth mode, biotech firm, has raised $9.0M in a venture round, according to a regulatory filing from the firm this week. Details on the funding have not been announced. Kleiner Perkins Caufield & Byers as well ...

San Diego-based Illumina said today that it has been served with a complaint alleging patent infringement, from Carlsbad-based Life Technologies. According to Illumina, it is being sued by Life Technologies, Applied Biosystems, a Russian re...

San Diego-based Zogenix, a pharmaceutical firm developing treatments for neuroscience disorders and pain, said Wednesday that it has completed a $51M, Series B preferred stock financing. The firm said that the round was led by Clarus Ventur...

Northridge-based Gamma Medica-Ideas, a developer of digital molecular imaging systems, said Tuesday that it has raised $24M in financing. The firm said the round, the first institutional funding for the firm, was made up of $14M in equity, ...

Irvine-based Quality Systems, a provider of IT products for the healthcare market, reported this morning that it has appointed Philip N. Kaplan as the firm's Chief Operating Officer, and added Craig A. Barbarosh to its board. Kaplan was mos...

La Jolla-based Celladon, a developer of treatments for heart failure and other cardiovascular diseases, has raised $21.8M out of a $24.6M funding round, according to a filing from the firm today. Details on the new funding round were not di...

Carpinteria-based ValenTx, a developer of medical devices for addressing morbid obesity, announced today that it has raised $22M in a Series B financing round. The round was led by SV Life Sciences, and also included Covidien Ventures, Sapi...

Irvine-based Visiogen, a developer of intraocular lens technology for treating cataract patients, is being acquired by Abbott in a deal worth $400M. According to Abbott, it will pay $400M in cash for VisioGen, whose intraocular lens technol...

San Diego-based Mabvax Pharmaceuticals, which is developing vaccines and human antibodies targeted at treating cancer, has gained $500,000 out of a $4M funding round, according to a regulatory filing from the firm. Mabvax had previously rai...

Carlsbad-based Life Technologies, a developer of biotechnology tools, announced this morning that it has entered into a definitive agreement to sell its ownership stake in its mass spectrometry joint venture, to Danaher for $450M. Danaher i...

San Diego-based Animal Cell Therapies, a biotech firm developing stem cell treatments for animals, has raised $1.1M in a funding round, according to a regulatory filing by the firm Monday. No details on the funding have been released. The f...

Carlsbad-based Aubrey, a startup developing wound care products that promote wound healing and burn care, has raised $3.87M in a $6.0M venture round, according to a regulatory filing from the firm Monday. Details on the funding have not bee...

San Diego-based Metabasis Therapeutics reported this morning that the firm's President, CEO, and Chief Scientific Officer, Mark Erion, is leaving the firm. According to Metabasis, Erion is leaving the firm for Merck, to become Vice Presiden...

Carlsbad-based Medsphere Systems, a developer of electronic health record software, announced Monday afternoon that the firm has raised $12M in a financing round. The round came from Azure Capital Partners, Epic Ventures, Thomas Weisel Vent...

Carpinteria-based ValenTX, a developer of treatments for obesity, has raised $20.28M in an equity funding round, according to a regulatory filing by the firm Thursday. Details on the funding have not been released by the company. ValenTx ha...

San Diego-based Ligand Pharmaceuticals reported Monday that it has acquired Connecticut-based Neurogen, a developer of small-molecule drugs to improve the lives of patients suffering from psychiatric and neurological disorders. Ligand said ...

San Diego-based MediciNova, a biotech firm developing small-molecule therapeutics, said Friday that it has reached an agreement with Alameda-based Avigen to merge with the firm. Medicinova said Avigen shareholders would receive either $1.24...

San Diego-based Palkion, a developer of oral drugs for treating anemia, has raised $2.5M in a funding round, according to a regulatory filing from the firm Monday. Details on the funding have not been released. The firm is backed by ProQues...

Escondido-based Datrix, a developer of portable devices for heart monitoring, has been acquired by medical devices firm IntriCon Corporation for approximately $2.5M. St. Paul, Minnesota-based IntriCon said the deal includes $1.225M in cash,...

Venture capital firm Domain Associates, which is based in San Diego and New Jersey, said Monday that it has closed a $500M fund focused on the life sciences industry. The firm said the fund, Domain Partners VIII, L.P., will continue to focu...

San Diego-based ChemNavigator, a developer of informatics tools for the pharmaceutical industry, has been acquired by scientific equipment firm Sigma-Aldrich. Financial terms of the buy were not disclosed. According to Sigma-Aldrich, the bu...

Irvine-based Spectrum Pharmaceuticals has acquired the remaining rights to RenaZorb, the firm's nanotechnology compound being used for treating hyperphosphatemia in patients with chronic kidney disease. The firm said it is paying $750,000 i...

San Diego-based Freedom Meditech, a developer of medical devices for measuring blood sugar in the diabetic, said today that it has raised a second tranche of funding in its Series A funding. Amount of the funding was not disclosed, however,...

Carpinteria-based Celerus Diagnostics, a developer of scientific equipment for the pathology lab market, said today that it plans to introduce a totally automated immunohistochemistry (IHC) staining system to the market next year. The firm ...

Fullerton-based scientific equipment firm Beckman Coulter announced today that it has acquired the lab-based diagnostics business of Olympus, in a deal worth approximately 76 billion Japanese yen in cash, or approximately $780M. Beckman, wh...

Irvine-based Cortex Pharmaceuticals, which is developing treatments for sleep apnea, reported this morning that it has received $2.0M in a Series F, convertible preferred stock financing from an unnamed, single institutional investor. The f...

Pasadena-based Replenish Inc. has quietly raised $10.25M in venture funding, according to a regulatory filing by the firm this week. No details on the firm have been disclosed, however, the firm describes itself as working on a "flexible dr...

San Diego-based aTyr Pharma, which is developing biopharmaceuticals focused on inflammation, autoimmune, hematopoietic and metabolic disorders, disclosed Tuesday that it has raised $12M in an additional funding round. The firm said the fund...

San Diego-based Epic Sciences, a stealth mode startup which appears related to the Scripps Research Institute, has quietly raised $2.5M in a funding round. Epic is developing analytical laboratory instruments. The funding for the firm was d...

San Diego-based Lithera, which is developing injectable treatments for fat tissue reduction, has raised $10M in a funding round. Source of the funding was not announced by the firm. Lithera, which was formerly known as Lipothera, is backed ...

San Diego's BeneChill, a firm developing medical devices for rapid, non-invasive cooling of patients for the treatment of cardiac arrest, stroke, or head injury, said Monday that it has raised $13.5M in a Series C financing round. The round...

Irvine-based Numira Biosciences, a contract research organization focused on high resolution imaging, has raised $3.2M in a funding round, according to a recent regulatory filing by the firm. No details on the funding have been announced by...

Covina-based StemCyte, a venture-backed operator of an umbilical cord blood bank, has scored $1M in a debt funding round, according to debt financing firm Agility Capital. Agility said that the senior secured growth capital loan closed in J...

San Diego-based DexCom, which develops continuous glucose monitoring systems for the hospital industry, said this week that it has named Eric Topol, M.D., to its board. Topol is the Director of the Scripps Translational Science Institute. D...

A spinout of the University of Southern California, Pivotal Biosciences, is benefiting from the approval of a $3.5M drug development project that was just approved by the National Cancer Institute, for developing a treatment for metastatic...

La Jolla-based Intellikine, a developer of small molecule drugs for the treatment of cancer, inflammation, and autoimmune diseases, said Wednesday that it has raised $51M in a financing round for the firm. The round was led by Novartis Biov...

Irvine-based Pegasus Biologics, a venture backed developer of collagen-based bioimplants for orthopedic, spine, and neurosurgery, has been acquired by Synovis Life Technologies, Inc. Synovis said that it has signed a definitive purchase agr...

San Diego-based Somaxon Pharmaceuticals reports today that the publicly held firm has received a $6M, private equity financing. The firm said that the funding came from its existing venture investors, including MPM Capital, Montreux Equity ...

Carlsbad-based Life Technologies, a developer of biotechnology tools and products, reported today that it is selling its SQL*LIMS laboratory information management software business to LabVantage Solutions, Inc. Financial terms of the dives...

San Diego-based Ambit Biosciences, a developer of small molecule profiling tools being used for biopharmaceuticals development, has raised $6.5M in an ongoing, debt round, according to a filing from the firm today. Details on the debt round...

San Diego-based Sorrento Therapeutics, a new biotechnology startup, has raised $2.3M in an equity funding round, according to a regulatory filing by the firm yesterday. Source of the funding was not disclosed. The firm is headed by Antonius...

San Diego-based Halozyme Therapeutics reported today that the firm has named H. Michael Shepard, Ph.D., as the firm's new Vice President of Discovery Research. According to Halozyme, Shepard was most recently at Receptor Biologix, where he ...

San Diego-based life sciences and scientific software developer Accelrys reported Monday that Scipio "Max" Carnecchia has joined the company as chief executive officer and president, effective immediately. Carnecchia has also been appointed...

San Diego-based Inovio Biomedical and Long Beach-based Cardigant Medical announced this morning that the two firms are in a commercial license, where Cardigant Medical will use Inovio's technology to develop intravascular catheters. Financi...

Pasadena-based Protabit, a brand new startup based on research from Caltech, and chemical giant Monsanto disclosed this morning that the two firms have entered into a two-year collaboration, to develop new tools for protein design and optim...

San Diego-based Illumina, which makes gene sequencing and other related life sciences equipment, said Wednesday afternoon that the firm is getting into the personal genome sequencing market. According to Illumina, it will offer complete cov...

Ventura-based VivoMetrics, which develops patient monitoring devices, said this week that it has completed a prototype of the firm's next generation LifeShirt product, which is used for remote monitoring of patient vital signs. According to...

Vista-based Aperio Technologies, which develops digital pathology products for the healthcare and life sciences industries, is reporting that it has filed a patent infringement lawsuit against Olympus America, Inc., Hamamatsu Corporation an...

San Diego-based CardioDynamics, a maker of cardiography products used for non-invasive assessment of cardiac output, is being acquired for $10M by SonoSite. According to Sonosite, it will pay $1.35 per share in cash for publicly held Cardi...

Santa Barbara-based TrueVision Systems, a developer of 3D visualization technology used for microsurgery, said this week that it has raised $1.2M in a convertible financing round, part of an effort which will raise $2M for the firm. TrueVis...

San Diego-based aFraxis, a stealth-mode firm developing treatments for Fragile X Syndome and autism, has raised $750,000 in a funding round, according to a regulatory filing by the firm Tuesday. Details on the funding have not been announce...

Carlsbad-based Alphatec Holdings, the parent firm of medical device firm Alphatec Spine, announced Friday that the firm has raised $10M in a private placement. According to the company, the funding came from Healthpoint Capital Partners II,...

Carlsbad-based Applied Biosystems announced Monday that the firm has shipped a number of new, mass spectrometry tools aimed at the laboratory market. According to the firm, which is a division of Life Technologies, the new tools are targete...

San Diego-based Metabasis Therapeutics, which is developing treatments for metabolic diseases, said Wednesday that it will cut approximately 85 percent, or 45 of its employees. According to the firm, the move was necessary because of "diffi...

Vista-based Ophthonix, which is developing high definition vision correction products, announced Tuesday afternoon that it has raised $25.9M in what it is calling a "Series AA" funding round. According to the firm, investors in the new roun...

Irvine-based biotechnology firm Spectrum Pharmaceuticals reports that it has won $4.3M in an arbitration over a dispute with Cell Therapeutics, over liabilities over joint venture expenses. According to the firm, $3.5M of the amount was ord...

Los Angeles-based Abraxis BioScience, a biotech firm focused on treatments for cancer, said Friday that it has hired on Marty J. Duvall as the firm's Senior Vice President, Global Marketing and International Commercial Operations. Duvall jo...

Irvine-based NeoMend, which is developing wound healing products, disclosed this week via a regulatory filing that it has raised $2.7M out of a $3.5M funding round for the company, consisting of a convertible note along with warrants conver...

La Jolla-based Aragon Pharmaceuticals reported Wednesday that it has raised $8M in a Series A financing. The firm, which is focused on small molecule therapeutics for treating hormone-resistant cancers, said that the financing was led by Th...

San Diego-based specialty pharmaceuticals firm Victory Pharma has been acquired by Atlanta-based Sciele Pharma, Sciele said this week. According to Schiele, it will pay $150M to acquire Victory Pharma, which is focused on acquiring, develop...

San Diego-based Metabasis Therapeutics, which develops biopharmaceuticals for treating metabolic diseases, said today as part of its quarterly results that it is hoping to raise capital in Q2 to fund the firm's operations. The firm--which s...

La Jolla-based Anaphore, a developer of protein therapeutics, announced today that it has raised an additional $13M in the firm's Series A preferred stock financing. According to the firm, the new funding brings the total round size to $38M...

Carlsbad-based Medsphere Systems, a venture-backed developer of open source electronic health records software, said Friday that it has named Irv Lichtenwald as its Chief Financial Officer. Lichtenwald previously served as CFO For Advent So...

San Diego-based Illumina, a developer of life sciences and genetic analysis systems, disclosed Tuesday that it has filed a patent infringement suit against competitor Affymetrix. According to Illumina, the suit--filed in the United States D...

Irvine-based Visiogen is reporting this morning that it has raised $40M in a financing round for its intraocular lens technology. The firm said the funding was led by Novartis Venture Fund, and also included investments from Technology Part...

Santa Barbara-based InTouch Health, a developer of telepresence robots for the healthcare market, said this week that it has named Gerry Popolow as the firm's Vice President of Clinical Services and Account Management. Popolow has served as...

Playa Vista-based X Prize Foundation is taking an unusual approach to fund its nonprofit efforts, and is auctioning off a complete gene sequencing to the highest bidder on eBay. The auction--which starts at $68,000--will give the winner a c...

San Diego-based NuVasive, a manufacturer of products used in the surgical treatment of spine disorders, announced Wednesday that it has agreed to acquire Cervitech, a New Jersey-based firm developing a cervical disc replacement device. NuVa...

Los Angeles-based Abraxis BioScience, a biotechnology firm focused on treatments for cancer and other illnesses, is the lead investor in a Maryland-firm developing technology for tissue protein analysis. According to Rockville, Maryland-bas...

Irvine-based Vision Solutions reported yesterday that the firm has signed on healthcare provider The Jackson Clinic as a customer. Financial impact of the win was not disclosed. Vision Solutions said that The Jackson Clinic is using the fir...

Long Beach-based Obagi Medical Products, which develops aesthetic and therapeutic skin care products, said Monday afternoon that the firm will stop selling its SoluCLENZ Rx Gel in pharmacies. The firm said that the company will instead focu...

Newport Beach-baed TriZetto Group, a developer of health care management software, said Monday that the firm has added the CareMore Health Plan as a customer. Financial impact of the deal was no disclosed. CareMore Health Plan is a provider...

Carlsbad-based Invitrogen, a manufacturer of diagnostic equipment for the life sciences industry, announced this morning that it has released a new product. According to Invitrogen, its new GIBCO OPTmizer T-cell Expansion SFM is targeted at...

The X PRIZE Foundation, the Playa Vista-based nonprofit using multimillion dollar prizes to drive innovation, said Thursday that the firm will announce the initial prize parameters for its $10M+, Healthcare X PRIZE next week. According to t...

San Diego-based La Jolla Pharmaceuticals, a publicly traded specialty pharmaceuticals firm, has received a dreaded "going concern" opinion from its auditor, Ernst & Young. The opinion--when an auditor decides that the firm being audited has...

San Diego-based Inovio Biomedical Corporation said yesterday that the firm has appointd Ng Tee Khiang to the firm's board. Khiang is co-founder, partner, and director of a number of firms, including Evia Capital Partners Pte. Ltd. and Evia ...

Aliso Viejo-based Cianna Medical is reporting today that the firm has completed a Series B funding round worth more than $10M. The firm, which is developing treatments for early stage breast cancer, said the funding comes from Emergent Medi...

Aliso Viejo-based LensX Lasers, a maker of cataract surgery devices, has raised $22.36M in a funding round, according to a recent regulatory filing. According to the filing, the funding came on March 19th, and included investors Versant Ven...

Calabasas-based Asprya, a provider of clinical information management systems for the healthcare market, said today that it has reorganized its management team. According to the firm, Bruce Miller, Chief Technology Officer of the firm and o...

La Jolla-based Travera Therapeutics, which is developing biopharmaceuticals based on RNA interference (RNAi) technology, said Thursday that it has raised $5M in a Series B financing round. The round was led by Morningside Venture Investment...

La Jolla-based TorreyPines Therapeutics, a biopharmaceuticals firm focused on small molecule compounds, said this week that it has reduced its work force to just three employees. The firm said the move came as it looks to evaluate strategic...

La Jolla-based Ambrx, which is developing protein and antibody drugs, said in a regulatory filing today that it has raised $10M. No details of the funding round have been disclosed. Ambrx has previously raised capital from 5AM Ventures, Mav...

San Diego-based Quidel, a developer of diagnostic tests for the healthcare industry, said Tuesday that it has cut approximately 10 percent of its work force, or 31 employees, in a corporate restructuring. According to Quidel, it made the cu...

San Diego-based Somaxon Pharmaceuticals, a specialty pharmaceuticals firm in the central nervous system therapeutic area, said Thursday afternoon that the firm has received a warning from the Nasdaq Stock Market. The warning--which is a pre...

San Dieog-based PURE Bioscience, a developer of an antimicrobial disinfectant, said Wednesday that it has licensed a distributor for its products in India. According to PURE Bioscience, the firm's products will be distributed under the bran...

San Diego-based Adventrx Pharmaceuticals, which was developing pharmaceuticals to improve existing cancer treatments, said late Friday that it will discontinue "substantially all" of its development activities and business operations. The f...

Irvine-based Relsys International, a developer of drug safety and risk management software for the health care industry, has been acquired by software giant Oracle. Oracle said this morning that it has agreed to acquire Relsys, which will b...

San Diego-based Advantar Laboratories, a provider of contract laboratory services to the drug development industry, has signed an agreement with UK-based firm NextPharma Technologies, a pharmaceutical product development, contract manufactu...

Irvine-based Cortex Pharmaceuticals, a developer of biopharmaceuticals for treating psychiatric disorders, neurological diseases and brain-mediated breathing disorders, said Thursday that it has cut half of its staff as part of a restructur...

Santa Barbara-based Innovative Micro Technology, a maker of micro-electromechanical (MEMS) systems, announced today that the firm has created a new division focused on life sciences. The firm said the new division will focus on developing m...

InstaMed, which operates a network for healthcare payment processing, said Tuesday that the firm has raised $6M in a growth equity financing. The firm, which has operations in Newport Beach and is headquartered in Philadelphia, said the rou...

Los Angeles-based Zynx Health, a developer of health care decision support software, said this morning that the firm has upgraded its AuthorSpace software. According to the firm, the new version of the software adds such features as PDF exp...

Irvine-based NeoMatrix, a developer of a noninvasive breast cancer screening device, said Friday that it has completed a C2 funding round, worth $15M. Investors in the round were not disclosed. According to the firm, the round was oversubsc...

San Diego-based Sangart, a biopharmaceuticals firm focused on the commercialization of oxygen therapeutics, said Thursday that it has raised $50M in a Series F funding round. Names of investors were not disclosed, however, the firm said the...

La Jolla-based Fate Therapeutics, a firm developing stem cell technology, said today that it has named Ken Batchelor, Ph.D., as the firm's Chief Scientific Officer. Batchelor joins the firm GlaxoSmithKline, where he was most recently Senior...

San Diego-based Victory Pharma has raised $45M in an equity financing round, the firm said Monday. The round was led by Essex Woodlands Health Ventures, and also included prior investor Ampersand Ventures. According to Victory Pharma, Scott...

Carlsbad-based Regulus Therapeutics, a biopharmaceuticals firm focused on microRNA-based therapeutics, announced this morning that it has raised $20M in a Series A funding round. The investment came from Alnylam Pharmaceuticals and Isis Pha...

Monrovia, California-based Xencor, which is developing antibodies to treat such things as Hodgkin lymphoma and inflammatory disease, said this morning that it has inked a technology license and evaluation agreement with Pfizer. According to...

San Diego-based Metabasis Therapeutics has hired on a new Vice President and Chief Financial Officer, the firm disclosed today. Metabasis, which is developing biopharmaceuticals for treating metabolic and other diseases, said that it has na...

Carlsbad-based Helixis, which develops tools for nucleic acid analysis, said Thursday that it has added Illumnia CEO Jay Flatley to the firm's board of directors. The company, which is venture backed by Domain Associates and Okapi Venture C...

San Diego-based XIFIN, a publisher of hosted revenue cycle management software for diagnostic laboratories, reported Tuesday that it has added two members to its executive staff. The company said it has hired Steve Zaniboni as chief financi...

Irvine-based CoreValve, a venture-backed developer of an aortic valve replacement market, has been acquired by Medtronic in a $700M deal, Medtronic said this morning. According to Medtronic, it will pay $700M plus additional contingent paym...

San Diego-based La Jolla Pharmaceutical Company has laid of a "substantial" number of the firm's personnel, and is looking to either shut down the business or sell the company, the firm said Thursday, after a failure of the firm's Phase 3 t...

Los Angeles-based Kythera Biopharmaceuticals, which is developing products for the aesthetic medicine market, disclosed this morning that it has received $10M as part of the firm's Series C funding round. According to Kythera, the round inc...

San Diego-based Cadence Pharmaceuticals, which licenses, develops, and commercializes biopharmaceuticals, said Tuesday that it has reached an agreement to raise approximately $86.6M from a group of venture capital investors. The publicly he...

Carpinteria-based Celerus Diagnostics, which is developing products focused on providing rapid cancer diagnostics, announced today that it has raised $5M in a Series C funding round. Investors in the new round were not disclosed. According ...

San Diego-based Mpex Pharmaceuticals said Tuesday that the firm has raised $27.5M in a Series D financing round. The firm, which is developing antibiotics, said that the round was led by Investor Growth Capital. Other investors in the firm ...

Carlsbad-based SynergEyes, a developer of hybrid contact lenses, announced Friday that the firm has raised $13.3M in a Series C funding round. SynergEyes said that the round was led by De Novo Ventures, and also included Bio-Star Private Eq...

San Diego-based Hollis-Eden Pharamceuticals, a developer of biopharmaceuticals, said Monday that the firm is cutting its workforce by approximately 33 percent, or 20 employees. According to the firm, the "aggressive" cost cutting plan is du...

Ventura-based Aquea Scientific, which develops a UVA/UVB sunscreen which can be washed on or applied in the shower, has quietly raised $10.955M in funding. The funding was first disclosed in the PricewaterhouseCOopers/NVCA MoneyTree venture...

San Diego-based Sequenom, a developer of genetic analysis products, said Monday afternoon that it has acquired SensiGen LLC, a biotechnology firm based in Ann Arbor, Michigan. Sequenom said it paid $8.7M for SensiGen, including earn-out mil...

San Diego-based Axikin Pharmaceuticals, a new startup focused on small molecule therapeutics for respiratory and inflammatory disease, announced Thursday that it has raised $3M in a Series A funding. The company, which is a spinout of Actim...

San Diego-based Nanogen, a developer of molecular diagnostics products, said today that it has received permission to investigate alternatives to a previously announced merger with the Elitech Group. Nanogen had originally announced its mer...

San Diego-based Metabasis Therapeutics, a biopharmaceuticals development firm, just announced this morning that it is cutting 38 employees, or approximately 43 percent of its employees as part of a corporate restructuring. Metabasis said th...

Los Angeles-based Abraxis Biosciences disclosed this morning that the firm's board has approved a plan to create a new company, Abraxis Health, Inc., which will focus on biomarkers and personalized medicine. According to Abraxis, the new fi...

San Diego-based Sequenom, a developer of genetic analysis products, is making a hostile bid for a competitor, EXACT Sciences Corporation, shortly after an offer was rejected by Exact's board. Sequenom said this morning that it has offered ...

Carlsbad-based Ablation Frontiers, a venture-backed provider of products for the treatment of atrial fibrillation, has been acquired by Medtronic for $225M. According to Medtronic, it will pay $225M plus additional, unspecified contingent p...

San Diego-based Illumina, a developer of life science analysis tools, said Monday that the firm's products have been selected by Duke University Medical Center. According to Illumina, researchers at the school will use its Genome Analyzer t...

La Jolla-based Anaphore has raised $25M in a Series A financing, the firm said Wednesday, in a funding led by 5AM Ventures, Versant Ventures, and Apposite Capital. The firm, which is developing biopharmaceuticals for treating immune-mediate...

Laguna Beach-based OrthAlign said Wednesday that the firm has raised $7.2M in a Series A funding round, in what looks to be the first announced Southern California venture deal in 2009. The funding was led by Research Corporation Technologi...

San Diego-based Illumina has hired on a new Senior Vice President of Operations, Bill Bonnar, the firm disclosed this morning. The firm, which develops life science products and services for the genomics market, said that Bonnar joins the c...

San Diego-based DexCom has appointed a new Chief Administrative Officer, the firm disclosed this morning, saying it had hired Steven R. Pacelli. The firm, which designs glucose monitoring systems for the healthcare industry, said that Pacel...

Los Angeles-based Healthshoppr, a startup developing an online appointment booking and ratings site for the healthcare market, launched its beta site Thursday. The site has launched starting with the wellness market, offering bookings of ma...

Carlsbad-based Medsphere is behind a new effort to help medical students learn about healthcare IT and clinical informatics, the firm disclosed this morning, and is supplying its products to the University of Oklahoma College of Nursing. Me...

Santa Barbara-based BioIQ, a provider of web-based, consumer health testing services, said last week that it has inked a deal to provide its services to Alere, a provider of health and wellness serviecs. According to BioIQ, the firms will w...

San Diego-based Vical Incorporated, a biopharmaceuticals firm focused on immunotherapeutics for cancer and DNA vaccines for infectious diseases, said Friday that it has cut 29 employees, or approximately 20 percent of the firm. According to...

San Diego-based Awarepoint, a developer of systems for tracking assets and patients in hospitals, has raised $13.3M in a Series D funding. The firm said the round was led by Cardinal partners, and also included Venrock and prior investor Av...

Los Angeles-based Abraxis BioScience, a biotechnology firm focused on compounds for treating cancer, said this morning that it has reached an agreement with AstraZeneca UK Limited to re-acquire rights to market the firm's ABRAXANE treatment...

Calabasas-based Aspyra, a provider of clinical information systems for the healthcare industry, has appointed Rodney Schutt as the firm's CEO. Schutt joins Aspyra from Luminetx, where he was Chief Operating Officer. Schutt has also served a...

San Diego-based Zacharon Pharmaceutical said today that it has raised $3.5M in a Series A financing for the firm's biopharmaceuticals technology. According to the firm, the financing came from Avalon Ventures LLC. The firm also said it has ...

Aliso Viejo-based Valeant Pharmaceuticals said today that it has acquired an Australian specialty pharmaceuticals firm, DermaTech Pty Ltd. Valeant said it paid approximately AU$19M ($12.5M US) for DermaTech, which develops products for the ...

San Diego-based Ardea Biosciences, which is developing small-molecule therapeutics for the treatment of HIV, gout, cancer and inflammatory diseases, announced Thursday that the firm has scored an $8M growth capital loan from Oxford Finance ...

Laguna Hills-based CODA Genomics, which is developing technology for engineering proteins, metabolic pathways and microorganisms for the life sciences, chemical, and biofuels market, said Tuesday that it is renaming itself Verdezyne, Inc. T...

San Fernando-based Precision Dynamics Corporation, a provider of identification and labeling products for the hospital and healthcare market, has acquired TimeMed Labeling Systems, which creates specialty healthcare labels, the firms said T...

Irvine-based Pegasus Biologics, which develops products for the soft tissue repair and wound care management market, said earlier this week that it has named Rob Cripe as its Vice President of Marketing and Product Development. Cripe joins ...

San Diego-based biopharmaceuticals firm Phenomix will receive $75M in an upfront payment, and up to $340M total, in a deal with Forest Laboratories, Inc., the firms said Thursday. According to the companies, they are in a definitive collabo...

San Diego-based NaviMedix said earlier this week that it has acquired TopLine Solutions, a provider of healthcare payment and collection services. Financial terms of the acquisition were not disclosed. NaviMedix operates a web-based network...

San Diego-based Phenomix Corporation, a biopharmaceuticals firm focused on small molecule drugs, has dropped its IPO bid, according to a filing by the company with the SEC this morning. Phenomix said that it has applied to withdraw its IPO,...

Ventura-based Vivometrics, maker of medical monitoring technology, has raised $19.917M in funding, according to numbers released by this week's PricewaterhouseCoopers/NVCA venture capital report. Details of the funding were not disclosed. V...

Carlsbad-based SkinMedica, a developer of cosmeceuticals for the dermatology field, has scored $27.5M in debt from two lenders. According to GE Healthcare Financial Services and BlueCrest Capital Finance, they have provided $27.5M in a seni...

The X Prize Foundation announced Thursday that it has received a grant from the Bill & Melinda Gates Foundation to develop a prize focused on the effective diagnosis of tuberculosis in the developing world. Amount of the grant was not discl...

San Diego-based Cytori Therapeutics disclosed earlier this week that it has scored a $15M loan facility from GE Healthcare Financial Services and Silicon Valley Bank. The firm, which develops products for the regenerative medicine market, s...

Aliso Viejo-based Valeant Pharmaceuticals International said Thursday that it has completed its acquisition of Coria Laboratories Ltd. The deal was worth $95M. Valeant had originally announced the acquisition of Coria Laboratories from its ...

Irvine-based Endologix, which develops medical devices for the minimally invasive treatment of abdominal aortic aneurysms, said Wednesday that it has received an unsolicited offer for the company from private equity firm Elliot Associates. ...

CoreValve Inc., a designer and manufacturer of artificial replacement components for the human heart, reported earlier this week that it has appointed Frank Fischer to its board of directors. The Irvine, Calif.-based company described Fisch...

Santa Ana-based Advanced Medical Optics is seeing an impact on it sales due to the economy, the firm disclosed this morning, saying it would lower its 2008 revenue guidance and EPS. According to AMO, it is now forecasting $1.17 billion to $...

Nexeon MedSystems, a newly formed company focused on developing stents and other medical devices, announced this morning that the firm has raised $24M in funding from SurModics, Inc., Guidant Corporation, and other private investors. The fi...

Santa Ana-based Advanced Medical Optics said this morning that it has received FDA approval on a medical device for opthalmic surgery. According to AMO, the U.S. Food and Drug Administration has granted premarket approval to the firm's Heal...

San Diego-based pharmaceuticals firm Ligand Pharmaceuticals said Thursday morning that it has entered into a definitive merger agreement to acquire Pharmacopeia. The deal is worth $70M. According to the firm, the deal is a stock-for-stock e...

San Diego-based Sequenom, a provider of genetic analysis products, said Tuesday that it has agreed to acquire the Center for Molecular Medicine (CMM), a clinical diagnostics laboratory based in Grand Rapids, Michigan. According to Sequenom,...

The Tech Coast Angels said this morning that the group has made an investment in Amplyx Pharmaceuticals, a drug development firm developing small molecule drugs. According to the Tech Coast Angels, it invested $289,000 in a Series A round f...

Freedom Meditech, a firm developing proprietary non-invasive ocular glucose measurement device for people with diabetes, has scored $380,000 in a equity investment. The round was disclosed by JumpStartup, an early stage venture acceleration...

Irvine-based Endologix, which develops medical devices for the minimally invasive treatment of aneurysms, said this morning that it has hired Gary I. Sorsher as the firm's Vice President of Quality. According to Endologix, Sorsher joins the...

Venture capital firm Sofinnova Ventures has hired on an Executive-in-Residence based in San Diego, the firm said Thursday. Sofinnova, which invests in early stage life sciences and IT firms, said it has appointed Lars Ekman, M.D., Ph.D. to ...

Van Nuys-based Microfabrica, which micro-fabricates three dimensional micro-devices, said Thursday that the firm has raised $22.5M in a Series B funding. The round was co-led by Versant Ventures and Interwest Partners, and also included pri...

Santa Barbara-based BioIQ, a startup providing web-linked health testing services, said this week that it has rolled out a new product targeted at corporate wellness testing. According to the firm, it has rolled out a new generation of the ...

San Diego-based medical device firm Ivera Medical Corporation has snagged a patent license from Becton, Dickenson and Company, the firm said this morning. Ivera announced that it is in an exclusive license agreement with BD, for the worldwi...

Last week, the organizers behind the Gold Coast Bio Center, a life sciences incubator forming along the 101 technology corridor, held a meeting to talk about the group's efforts to tap into the wealth of experience in the area in the biotec...

San Diego-based Somaxon Pharmaceuticals said today that it has appointed Richard W. Pascoe as the firm's President and CEO. Pascoe will also serve as a director of the company. Pascoe was most recently at ARAID Pharmaceuticals, where he was...

Aliso Viejo-based Valeant Pharmaceuticals International, which develops specialty pharmaceuticals, said Monday that it has agreed to sell the firm's business operations in Western Europe and Eastern Europe, including Russia. The firm said t...

Versant Ventures, a Newport Beach- and Menlo Park-based venture capital fund, announced today that it has closed Versant Venture Capital IV, L.P. at $500M. The fund brings Versant's total under management to $1.6 billion, in the areas of bi...

Poway-based Biologics Process Development Incorporated, a provider of contract laboratory services for the biotechnology industry, has been acquired by an Indian biopharmaceuticals firm, Intas Biopharmaceuticals Ltd. According to the firms,...